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Agkistrodon platelet aggregation inhibitor

from Agkistrodon halys snake venom; MW 14,000

Also Known As:

AgPAI; Applaggin

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Complex Mixtures: 1906
- Venoms: 4328
  - Snake Venoms: 1139
    - Viper Venoms: 122
      - Crotalid Venoms: 67
        Agkistrodon platelet aggregation inhibitor: 1
Biological Factors: 2472
- Biological Toxins: 20
  - Venoms: 4328
    - Snake Venoms: 1139
      - Viper Venoms: 122
        Crotalid Venoms: 67
        Agkistrodon platelet aggregation inhibitor: 1

Related Diseases

1.	Thrombosis (Thrombus) 11/01/1993 - "Thrombus weight was greater in control vessels (44.2 +/- 7.0 mg) vs. thrombus weight after applaggin (11.2 +/- 2.4 mg). " 11/01/1993 - "Time for occlusive thrombus development was 125.6 +/- 15.2 min. One of the seven left carotid arteries occluded after applaggin. " 11/01/1993 - "Applaggin, an inhibitor of platelet aggregation via binding to the glycoprotein IIb/IIIa receptor, was examined in an anesthetized canine model of arterial thrombosis formation secondary to arterial wall injury. "
2.	Carotid Artery Thrombosis 11/01/1993 - "The results demonstrate that applaggin possesses an antithrombotic effect in the experimental model of canine carotid artery thrombosis." 11/01/1993 - "Prevention of experimental carotid artery thrombosis by applaggin."

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