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tiflamizole

structure in first source

Also Known As:

4,5-bis(4-fluorophenyl)-2-((1,1,2,2-tetrafluoroethyl)sulfonyl)-1H-imidazole

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Halogenated Hydrocarbons: 42
    - Fluorinated Hydrocarbons: 4
      - Fluorocarbons: 1209
        tiflamizole: 4
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Imidazoles: 150
      - tiflamizole: 4

Related Diseases

1.	Arthritis (Polyarthritis) 09/01/1985 - "One of the compounds, 4,5-bis(4-fluorophenyl)-2-[(1,1,2,2-tetrafluoroethyl)-sulfonyl]-1H- imidazole (8d, tiflamizole), was found to be 8 times as potent as indomethacin in the rat adjuvant induced arthritis assay and is presently undergoing clinical trial as an antiarthritic drug." 07/01/1987 - "On the other hand, indomethacin, benoxaprofen, piroxicam, and tiflamizole, which are cyclo-oxygenase inhibitors in prostaglandin synthesis, had no effect on anti-type II collagen antibody titre, but suppressed the established lesion of the arthritis without causing an apparent rebound of the arthritis after withdrawal of the drug treatment. "
2.	Edema (Dropsy) 08/01/1987 - "In contrast, administration of high doses of cyclooxygenase inhibitors (indomethacin, piroxicam, naproxen, ibuprofen, meclofenamic acid and tiflamizole) did not affect AA-induced hind paw edema. "
3.	Rheumatoid Arthritis 07/01/1984 - "Tiflamizole elimination from plasma in rheumatoid arthritis."

Related Drugs and Biologics

1.	Indomethacin (Indometacin)
2.	Cyclooxygenase Inhibitors
3.	Piroxicam (Feldene)
4.	Collagen Type II (Type II Collagen)
5.	Prostaglandins
6.	Naproxen (Naprosyn)
7.	Meclofenamic Acid (Meclofenamate)
8.	Ibuprofen (Motrin)
9.	imidazole
10.	benoxaprofen