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MK 0641
combination of above cpds
Also Known As:
MK-0641; Pediazole; Erythromycin, 2-amino-5-((aminoacetyl)methylamino)-2,3,5-trideoxy-1-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-beta-L-lyxo-heptopyranosyl)-, (1alpha,2beta,2aalpha,3aalpha)-
Networked:
6
relevant articles (
0
outcomes,
2
trials/studies)
Drug Context: Research Results
Pharmaceutical Preparations
Drug Combinations: 5337
MK 0641: 6
Organic Chemicals: 133
Amines: 4871
Aniline Compounds: 46
Sulfanilamides: 40
Sulfisoxazole: 206
MK 0641: 6
Amides: 2428
Sulfonamides: 2809
Benzenesulfonamides: 153
Sulfisoxazole: 206
MK 0641: 6
Sulfanilamides: 40
Sulfisoxazole: 206
MK 0641: 6
Hydrocarbons: 1713
Cyclic Hydrocarbons: 97
Aromatic Hydrocarbons: 291
Benzene Derivatives: 17
Benzenesulfonamides: 153
Sulfisoxazole: 206
MK 0641: 6
Lactones: 1549
Polyketides: 231
Macrolides: 4391
Erythromycin: 3910
MK 0641: 6
Sulfur Compounds: 278
Sulfones: 534
Sulfonamides: 2809
Benzenesulfonamides: 153
Sulfisoxazole: 206
MK 0641: 6
Sulfanilamides: 40
Sulfisoxazole: 206
MK 0641: 6
Related Diseases
1.
Otitis Media
02/01/1991 - "
[An open randomized trial, Pediazole versus cefaclor in the treatment of acute otitis media in children].
"
02/01/1990 - "
In a prospective randomized open study, 111 young children with otitis media were orally treated during 10 days with Pediazole (50 mg/kg/day in 3 divided doses) or amoxicillin + clavulanic acid (40 mg/kg/day in 3 or 4 divided doses) for efficacy and safety evaluation.
"
02/01/1990 - "
In conclusion, Erythromycin sulfisoxazole combination (Pediazole) fits in with current epidemiological profile of Acute Otitis Media and represents a therapy of choice in this indication.
"
01/01/1988 - "
A 3-year-old female receiving Pediazole (erythromycin ethylsuccinate and sulfisoxazole) for tonsillitis and otitis media developed severe hemolytic anemia.
"
12/01/1990 - "
Children who suffer from recurrent episodes of acute otitis media may benefit from one of the three following prescriptions: amoxicillin + clavulanate (Augmentin), or an oral cephalosporin, or the erythromycin + sulfisoxazole combination (Pediazole).
"
2.
Tonsillitis
01/01/1988 - "
A 3-year-old female receiving Pediazole (erythromycin ethylsuccinate and sulfisoxazole) for tonsillitis and otitis media developed severe hemolytic anemia.
"
3.
Otitis Media with Effusion
03/01/1986 - "
To determine whether antimicrobial therapy is of value in the treatment of chronic otitis media with effusion (secretory otitis media), we treated 1,429 4- to 8-year-old children--2224 affected ears--with a fixed regimen of an antibiotic mixture (Pediazole) for 10 days and a decongestant (Novafed) for 30 days.
"
4.
Infections
01/01/1982 - "
Alternatives to ampicillin for middle ear infection are trimethoprim-sulfamethoxazole (Bactrim, Septra), erythromycin-sulfonamide (Pediazole), and cefaclor (Ceclor).
"
5.
Hemolytic Anemia
01/01/1988 - "
A 3-year-old female receiving Pediazole (erythromycin ethylsuccinate and sulfisoxazole) for tonsillitis and otitis media developed severe hemolytic anemia.
"
Related Drugs and Biologics
1.
Amoxicillin-Potassium Clavulanate Combination (Co-amoxiclav)
2.
Cefaclor (Ceclor)
3.
Sulfisoxazole (Sulfafurazole)
4.
Erythromycin (Erycette)
5.
Clavulanic Acid (Potassium Clavulanate)
6.
Sulfamethoxazole Drug Combination Trimethoprim (Co-Trimoxazole)
7.
Erythromycin Ethylsuccinate (E-Mycin E)
8.
Nasal Decongestants (Decongestants)
9.
Sulfonamides
10.
Cephalosporins (Cephalosporin Antibiotics)
Related Therapies and Procedures
1.
Therapeutics