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desciclovir
active prodrug of acyclovir
Also Known As:
2-((2-amino-9H-purin-9-yl)methoxy)-ethanol; 2-amino-9-(2-hydroxyethyl)methyl-9H-purine; 6-deoxyacyclovir; BW A515U
Networked:
9
relevant articles (
1
outcomes,
3
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Purines: 651
Purinones: 2
Hypoxanthines: 1
Guanine: 1793
Acyclovir: 4814
desciclovir: 9
Related Diseases
1.
Epstein-Barr Virus Infections
01/01/1990 - "
The histological features of HL were significantly diminished in patients on desciclovir, and cytochemical, in situ hybridization, and ultrastructural studies showed that EBV infection was eliminated or dramatically reduced in the desciclovir group only.
"
01/01/1990 - "
Efficacy of desciclovir in the treatment of Epstein-Barr virus infection in oral hairy leukoplakia.
"
01/01/1990 - "
The efficacy of desciclovir, an analog of acyclovir, in eliminating lesions of oral hairy leukoplakia (HL) and suppressing Epstein-Barr virus (EBV) infection was evaluated in a double-blind, placebo-controlled study of 14 patients.
"
2.
Hairy Leukoplakia
01/01/1990 - "
Efficacy of desciclovir in the treatment of Epstein-Barr virus infection in oral hairy leukoplakia.
"
01/01/1990 - "
The efficacy of desciclovir, an analog of acyclovir, in eliminating lesions of oral hairy leukoplakia (HL) and suppressing Epstein-Barr virus (EBV) infection was evaluated in a double-blind, placebo-controlled study of 14 patients.
"
3.
Hepatitis
03/01/1987 - "
The efficient hepatic conversion of 6-deoxyacyclovir to the active antiviral drug, acyclovir, provides a rationale for trials of oral 6-deoxyacyclovir in the treatment of chronic type B hepatitis.
"
08/29/1988 - "
For patients with chronic hepatitis B e (HBe)-positive hepatitis, long-term results of pilot studies with lymphoblastoid interferon-alpha, acyclovir, or a combination, and of a randomized controlled trial of interferon/desciclovir combination therapy are presented.
"
4.
Herpes Zoster
11/01/1987 - "
Open study of 2-amino-9-(hydroxyethoxymethyl)-9H-purine (desciclovir) in the treatment of herpes zoster.
"
11/01/1987 - "
An oral pro-drug of acyclovir, 2-amino-9-(2-hydroxyethoxymethyl)-9H-purine (desciclovir) was evaluated in an open study comprising of 20 patients with herpes zoster.
"
5.
Chronic Hepatitis B
01/01/1986 - "
A pilot study of BW A515U (6-deoxyacyclovir) in chronic hepatitis B virus infection.
"
08/29/1988 - "
For patients with chronic hepatitis B e (HBe)-positive hepatitis, long-term results of pilot studies with lymphoblastoid interferon-alpha, acyclovir, or a combination, and of a randomized controlled trial of interferon/desciclovir combination therapy are presented.
"
Related Drugs and Biologics
1.
Acyclovir (Aciclovir)
2.
Prodrugs
3.
Antiviral Agents (Antivirals)
4.
Interferon-alpha (Interferon Alfa)
5.
Vidarabine (Vira-A)
6.
Interferons
7.
Idoxuridine (Stoxil)
8.
Bromodeoxyuridine (BrdU)
9.
Adenosine Monophosphate (AMP)
10.
Famciclovir (Famvir)
Related Therapies and Procedures
1.
Therapeutics