fusarin C

structure given in first source

Also Known As:

2-ethylidene-11-(4-hydroxy-4-(2-hydroxyethyl)-2-oxo-6-oxa-3-azabicyclo(3.1.0)hex-1-yl)-4,6,10-trimethyl-11-oxo-3,5,7,9-undecatetraenoic acid methyl ester; 3,5,7,9-Undecatetraenoic acid, 2-ethylidene-11-((1R,4S,5R)-4-hydroxy-4-(2-hydroxyethyl)-2-oxo-6-oxa-3-azabicyclo(3.1.0)hex-1-yl)-4,6,10-trimethyl-11-oxo-, methyl ester, (2E,3E,5E,7E,9E)-

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Acyclic Hydrocarbons
    - Alkenes: 265
      - Polyenes: 164
        fusarin C: 5

Experts

1.	Bonefeld-Jørgensen, E C: 1 article (08/2011)
2.	Giese, H: 1 article (08/2011)
3.	Hansen, F T: 1 article (08/2011)
4.	Nielsen, A K: 1 article (08/2011)
5.	Purup, S: 1 article (08/2011)
6.	Sondergaard, T E: 1 article (08/2011)
7.	Sørensen, J L: 1 article (08/2011)

Related Diseases

1.	Esophageal Neoplasms (Esophageal Cancer) 06/01/1985 - "Fusarin C, a fungal metabolite, was recently isolated and identified from corn meal inoculated with Fusarium moniliforme which was one of the most common fungi associated with corn in Linxian county, a high-incidence area of esophageal cancer. " 08/28/2011 - "Fusarin C is a mycotoxin produced by several Fusarium species and has been associated with esophageal cancer due to its carcinogenic effects. " 09/01/1985 - "A new mutagen, Fusarin C has been recently isolated and identified from corn meal inoculated with Fusarium moniliforme, one of the most common fungus pollutant of corn in Linxian County, a high-risk area of esophageal cancer. "
2.	Chromosome Aberrations (Chromosome Abnormalities) 06/01/1985 - "In the presence of S-9 mix, fusarin C significantly increased the number of revertants in Salmonella typhimurium TA 100, and induced SCE, micronuclei, chromosome aberrations and 6-TG resistant mutants in V79 cells. " 09/01/1985 - "Fusarin C significantly induced sister chromatid exchange (SCE), micronucleus increase, chromosome aberrations, and 6-thioguanine resistant mutants in V 79 cells in the presence of microsomal preparations. "
3.	Neoplasms (Cancer) 11/01/1986 - "In neither of these models did fusarin C act as a cancer initiator. " 11/01/1986 - "The cancer initiating potential of fusarin C, a mutagen produced by Fusarium moniliforme strain MRC 826 was investigated on mouse skin using 12-O-tetradecanoylphorbol-13-acetate as promoter. "
4.	Carcinoma (Carcinomatosis) 01/01/1992 - "[Fusarin C induced esophageal and forestomach carcinoma in mice and rats]." 01/01/1992 - "The present work demonstrated that Fusarin C can induce esophageal and forestomach carcinoma in DBA mice and Wistar rats thus further substantiating the carcinogenicity of this mycotoxin."
5.	Breast Neoplasms (Breast Cancer) 08/28/2011 - "Here, we report that fusarin C stimulates growth of the breast cancer cell line MCF-7. " 08/28/2011 - "Fusarin C acts like an estrogenic agonist and stimulates breast cancer cells in vitro."

Related Drugs and Biologics

1.	Mycotoxins
2.	Mutagens
3.	Thioguanine (Tioguanine)
4.	Environmental Pollutants (Pollutants, Environmental)