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avicularin

from Polygonum aviculare L.; RN given refers to L-isomer

Networked: 16 relevant articles (2 outcomes, 3 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Benzopyrans: 195
      - Chromones: 159
        Flavonoids: 9773
        avicularin: 16
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzopyrans: 195
      - Chromones: 159
        Flavonoids: 9773
        avicularin: 16

Experts

1.	Gupta, Girdhari Lal: 1 article (02/2022)
2.	Samant, Nikita Patil: 1 article (02/2022)
3.	Kong, Ling-Yi: 1 article (10/2021)
4.	Sun, Ming-Hui: 1 article (10/2021)
5.	Yang, Lei: 1 article (10/2021)
6.	Yin, Wei-Feng: 1 article (10/2021)
7.	Zou, Zi-Ling: 1 article (10/2021)
8.	Amadi, Joy A: 1 article (02/2021)
9.	Amadi, Peter U: 1 article (02/2021)
10.	Njoku, Uche C: 1 article (02/2021)

Related Diseases

1.	Inflammation (Inflammations) 02/01/2023 - "The purpose of this research is to explore the inhibitory effect of avicularin (AL) on macrophage M1 polarization, by which it ameliorates inflammation, thus alleviating implant instability. " 06/01/2023 - "Hepatoprotective effect of avicularin on lead-induced steatosis, oxidative stress, and inflammation in mice associated with the MAPK/HSP60/NLRP3 and SREBP1c pathway." 10/01/2021 - "We aim to investigate avicularin to protect cartilage extracellular matrix degradation (ECM) and suppresses inflammation both in rat and human chondrocytes. " 11/01/2023 - "Avicularin alleviates acute liver failure by regulation of the TLR4/MyD88/NF-κB and Nrf2/HO-1/GPX4 pathways to reduce inflammation and ferroptosis." 10/01/2021 - "Taken together, our results indicate that avicularin suppresses cartilage extracellular matrix degradation and inflammation via TRAF6/MAPK activation by targeting TRAF6. "
2.	Hepatocellular Carcinoma (Hepatoma) 06/01/2019 - "Avicularin ameliorates human hepatocellular carcinoma via the regulation of NF‑κB/COX‑2/PPAR‑γ activities."
3.	Osteosarcoma (Osteogenic Sarcoma) 05/28/2020 - "This study aimed to investigate the effects of avicularin on bradykinin-treated MG-63 human osteoblastic osteosarcoma cells in vitro. " 05/28/2020 - "CONCLUSIONS Avicularin reduced the expression of inflammatory cytokines and the levels of markers of oxidative stress in MG-63 human osteoblastic osteosarcoma cells in vitro." 05/28/2020 - "Avicularin Reduces the Expression of Mediators of Inflammation and Oxidative Stress in Bradykinin-Treated MG-63 Human Osteoblastic Osteosarcoma Cells."
4.	Type 2 Diabetes Mellitus (MODY) 11/01/2019 - "In this study, the hypoglycemic effect of avicularin (quercetin-3-O-α-arabinofuranoside), a flavonoid glycoside commonly found in natural plants and fruits, was determined in a high fat diet/streptozotocin induced type 2 diabetes mouse model. "
5.	Rheumatoid Arthritis 12/01/2018 - "The present study aimed to investigate the effect of avicularin on rheumatoid arthritis (RA) in vitro, and additionally explore the molecular mechanism. " 12/01/2018 - "Protective effect of avicularin on rheumatoid arthritis and its associated mechanisms."

Related Drugs and Biologics

1.	Flavonoids
2.	Glycosides
3.	Streptozocin (Streptozotocin)
4.	Hypoglycemic Agents (Hypoglycemics)
5.	Bradykinin
6.	Polyphenols
7.	Incretins
8.	TNF Receptor-Associated Factor 6 (TRAF6)
9.	Proanthocyanidins (Procyanidins)
10.	Brain-Derived Neurotrophic Factor (BDNF)

Related Therapies and Procedures

1.	Chinese Traditional Medicine (Traditional Chinese Medicine)