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N-phenyl-N'-3-hydroxyphenylthiourea

Also Known As:

PTU 23; PTU-23

Networked: 4 relevant articles (1 outcomes, 0 trials/studies)

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Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amides: 2428
  - Urea: 15015
    - Thiourea: 362
      - Phenylthiourea: 102
        N-phenyl-N'-3-hydroxyphenylthiourea: 4
- Sulfur Compounds: 278
  - Thiourea: 362
    - Phenylthiourea: 102
      - N-phenyl-N'-3-hydroxyphenylthiourea: 4

Related Diseases

1.	Carcinoma (Carcinomatosis) 05/01/1983 - "PTU-23, an effective in vivo wide-range enterovirus inhibitor, suppresses the reproduction of encephalomyocarditis (EMC) virus in Krebs-II ascites carcinoma cells at concentrations of 20-50 micrograms/ml, not affecting the cellular synthetic processes. " 05/01/1983 - "PTU-23, a selective inhibitor of the reproduction of encephalomyocarditis (EMC) virus in Krebs-II ascites carcinoma cells, counteracts the virus-induced shut-off of the host-cell protein synthesis reducing it from 32% to 19%. "
2.	Ascites 05/01/1983 - "PTU-23, an effective in vivo wide-range enterovirus inhibitor, suppresses the reproduction of encephalomyocarditis (EMC) virus in Krebs-II ascites carcinoma cells at concentrations of 20-50 micrograms/ml, not affecting the cellular synthetic processes. " 05/01/1983 - "PTU-23, a selective inhibitor of the reproduction of encephalomyocarditis (EMC) virus in Krebs-II ascites carcinoma cells, counteracts the virus-induced shut-off of the host-cell protein synthesis reducing it from 32% to 19%. "
3.	Infections 01/01/1974 - "Under the action of N-phenyl-N'-3-hydroxyphenylthiourea (no. 23) and N-phenyl-N'-4-carboxy-5-hydroxyphenylthiourea (no. 20) a two- to threefold reduction in mortality was observed, as well as an appreciable delay in the course of the disease (mean effective dose, lengthening by 2 to 6 days) after infection with Coxsackie viruses B1, B3, and A7. "
4.	Body Weight (Weight, Body) 01/01/1986 - "PTU-23 was administered subcutaneously in doses of 200, 400 and 800 mg/kg body weight during 6 consecutive days. "

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)