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bis(2,4,5- trichloro- 6- carbopentoxyphenyl)oxalate

Also Known As:

CPPO

Networked: 7 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Acyclic Acids
    - Dicarboxylic Acids: 108
      - Oxalates: 2497
        bis(2,4,5-trichloro-6-carbopentoxyphenyl)oxalate: 7

Experts

1.	Liu, Yang: 1 article (03/2022)
2.	Song, Shuyan: 1 article (03/2022)
3.	Wang, Yinghui: 1 article (03/2022)
4.	Zhang, Hongjie: 1 article (03/2022)
5.	Ding, Hui: 1 article (01/2022)
6.	Huang, Guodong: 1 article (01/2022)
7.	Li, Weiping: 1 article (01/2022)
8.	Li, Zongyang: 1 article (01/2022)
9.	Ma, Guanghui: 1 article (01/2022)
10.	Peng, Yaonan: 1 article (01/2022)

Related Diseases

1.	Neoplasms (Cancer) 03/01/2022 - "Herein, we designed a cascade-responsive ROS nanobomb (ZnO2@Ce6/CaP@CPPO/BSA, designated as Z@Ce6/CaP@CB) with domino effect and without external stimulation for the specific generation of multiple powerful ROS storms at the tumor site. " 01/01/2021 - "1 O2 produced by PFODBT@CPPO induced cancer cell necrosis and promoted the release of damage-related molecular patterns, thereby evoking immunogenic cell death (ICD)-associated immune responses through ROS-based oxidative stress. " 03/01/2022 - "On the other hand, the generation of large amounts of exogenous H2O2 can cause oxidative damage to tumor cells and further activate bis[2,4,5-trichloro-6-(pentyloxycarbonyl)phenyl] oxalate (CPPO)-mediated chemiexcited photodynamic therapy. " 01/01/2021 - "For the nanoplatform of CPPO@porphyrin-MOF@Cancer cell membrane-GOD (C1@M@C2G), the ferric ion-linked porphyrin-MOF can trigger a Fenton reaction to reach CDT, the carried CPPO as an energy donor is used to excite a photo-sensitive porphyrin-MOF in situ to generate singlet oxygen (1O2) for PDT, GOD catalyzes glucose into H2O2 and gluconic acid to realize starvation therapy, and the cancer cell membrane wrapped onto the nanoparticle plays a key role in homologous targeting, which is conducive to achieving better therapeutic effects. "
2.	Drug-Related Side Effects and Adverse Reactions 09/01/2016 - "VA MedSAFE is a comprehensive pharmacovigilance program focused on the detection, assessment, and prevention of adverse drug events, and CPPO is dedicated to improving safe and appropriate medication use by supporting and expanding clinical pharmacy practice. "
3.	Acute Kidney Injury (Acute Renal Failure) 01/01/2023 - "We report the "water-in-oil-in-water" preparation of kidney injury molecule-1-targeting supramolecular chemiluminescence (CL) reporters (PCCS), consisting of L-serine-modified poly(lactic-co-glycolic) acid (PLGA)-encapsulated peroxyoxalate (CPPO), chlorin e6 (Ce6) and superoxide dismutase (SOD), for early diagnosis and amelioration of acute kidney injury (AKI). "
4.	Disease Progression 05/01/2019 - "In late 2016, the Department of Veterans Affairs (VA) Pharmacy Benefits Management Clinical Pharmacy Practice Office (CPPO) partnered with the VA HIV, Hepatitis, and Related Conditions Program with the central priority of expanding veteran access to novel HCV treatments and timely cure to ultimately prevent morbidity and mortality associated with HCV disease progression. "
5.	Starvation 01/01/2021 - "For the nanoplatform of CPPO@porphyrin-MOF@Cancer cell membrane-GOD (C1@M@C2G), the ferric ion-linked porphyrin-MOF can trigger a Fenton reaction to reach CDT, the carried CPPO as an energy donor is used to excite a photo-sensitive porphyrin-MOF in situ to generate singlet oxygen (1O2) for PDT, GOD catalyzes glucose into H2O2 and gluconic acid to realize starvation therapy, and the cancer cell membrane wrapped onto the nanoparticle plays a key role in homologous targeting, which is conducive to achieving better therapeutic effects. "

Related Drugs and Biologics

1.	Therapeutic Uses
2.	Singlet Oxygen
3.	Photosensitizing Agents (Photosensitizers)
4.	Superoxide Dismutase
5.	Serine (L-Serine)
6.	Prodrugs
7.	Porphyrins
8.	Oxalates
9.	Glucose (Dextrose)
10.	Polylactic Acid-Polyglycolic Acid Copolymer

Related Therapies and Procedures

1.	Therapeutics
2.	Photochemotherapy (Photodynamic Therapy)