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isostearic acid

Also Known As:

2-methyl-heptadecanoic acid; isostearate

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Lipids: 114793
- Fatty Acids: 27405
  - Stearic Acids: 44
    - isostearic acid: 5

Experts

1.	Azukizawa, H: 1 article (04/2009)
2.	Inui, S: 1 article (04/2009)
3.	Katayama, I: 1 article (04/2009)

Related Diseases

1.	Psoriasis (Pustulosis Palmaris et Plantaris) 06/01/2023 - "We then tested the substances in vivo using the imiquimod/isostearate model of psoriasis where the 2' ester was the most active at 0.06-0.12 mg/kg (approximately 0.1 µmol/kg), improving skin score, body weight and cytokine levels (TNFα, IL-17A, IL-17F, IL-6, IL-1β, NLRP3 and IL-23A). "
2.	Inflammation (Inflammations) 04/01/2023 - "Despite high imiquimod skin levels throughout the animal, inflammation was only apparent in the treated areas and was less severe than in isostearic acid groups. " 04/01/2023 - "Comparing cream formulations containing isostearic acid, imiquimod and the combination, we observed that isostearic acid causes skin inflammation within 2 days, whereas imiquimod requires up to 5 days for initial signs. "
3.	Hemolysis 04/15/1984 - "The mechanism of inhibition of viral hemolysis by isostearate involves the inactivation of viral hemolytic activity per se, since isostearate neither inhibited viral hemagglutination nor rendered erythrocytes significantly less susceptible to hemolysis. " 04/15/1984 - "Furthermore, the concentration dependence of hemolysis inhibition by isostearate was biphasic, increasing sharply at the critical micelle concentration from a linear relationship below that concentration. " 04/15/1984 - "cis-Unsaturated fatty acids such as oleate, as well as the methyl-branched isostearate, completely inhibited viral hemolysis at concentrations as low as 5-10 micrograms/ml, whereas the saturated, normal acids such as palmitate and stearate were comparably inhibitory only at 2-5 times those concentrations. "
4.	Cheilitis 04/01/2009 - "Recurrent contact cheilitis because of glyceryl isostearate, diisostearyl maleate, oleyl alcohol, and Lithol Rubine BCA in lipsticks."
5.	Body Weight (Weight, Body) 06/01/2023 - "We then tested the substances in vivo using the imiquimod/isostearate model of psoriasis where the 2' ester was the most active at 0.06-0.12 mg/kg (approximately 0.1 µmol/kg), improving skin score, body weight and cytokine levels (TNFα, IL-17A, IL-17F, IL-6, IL-1β, NLRP3 and IL-23A). "

Related Drugs and Biologics

1.	Imiquimod (Aldara)
2.	Oleic Acid (Oleate)
3.	Cytokines
4.	Stearates
5.	Palmitates
6.	Micelles
7.	Lipids
8.	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)
9.	Esters
10.	Acids