hemoglobin Saint Jacques

Ala replaced by Thr at position alpha2 beta2 140(H18); high oxygen-affinity variant with altered bisphosphoglycerate binding

Also Known As:

Hb Saint-Jacques; Hb St. Jacques; Hemoglobin Saint Jacques

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

1.	Polycythemia (Erythrocytosis) 01/01/1984 - "[Erythrocytosis due to a high-affinity hemoglobulin: mutant hemoglobin Saint-Jacques beta 140 (H18) Ala----Thr with a change in the 2,3-diphosphoglycerate binding site]."
2.	primary familial and congenital Polycythemia 01/01/1984 - "In this report we describe a new variant with familial erythrocytosis: hemoglobin Saint-Jacques beta 140 (H18) Ala----Thr, whose main abnormality is a defect in organic phosphate binding in the central cavity between to two beta chains. "

1.	2,3-Diphosphoglycerate (2,3 Bisphosphoglycerate)
2.	Phosphates (Orthophosphate)