neriifolin

structure in first source; RN given refers to alpha-L-glucopyranosyl(3beta,5beta)-isomer

Also Known As:

neriifolin, (3beta,5alpha)-isomer; neriifolin, beta-D-glucopyranosyl cpd (3beta,5beta)-isomer

Networked: 6 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Fused-Ring Compounds
  - Steroids: 70059
    - Cardanolides
      - Cardiac Glycosides: 1002
        Cardenolides: 137
        neriifolin: 6

Experts

1.	Amend, N: 1 article (10/2021)
2.	Thiermann, H: 1 article (10/2021)
3.	Wille, T: 1 article (10/2021)
4.	Worek, F: 1 article (10/2021)
5.	Deng, Fan: 1 article (07/2017)
6.	Pan, Li: 1 article (07/2017)
7.	Wang, Chunxia: 1 article (07/2017)
8.	Zhang, Yuming: 1 article (07/2017)
9.	Zhao, Wanlu: 1 article (07/2017)
10.	Zhou, Xia: 1 article (07/2017)

Related Diseases

1.	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 07/05/2006 - "In subsequent whole-animal studies, we found that neriifolin provided significant neuroprotection in a neonatal model of hypoxia/ischemia and in a middle cerebral artery occlusion model of transient focal ischemia. "
2.	Ischemia 07/05/2006 - "In subsequent whole-animal studies, we found that neriifolin provided significant neuroprotection in a neonatal model of hypoxia/ischemia and in a middle cerebral artery occlusion model of transient focal ischemia. "
3.	Hypoxia (Hypoxemia) 07/05/2006 - "In subsequent whole-animal studies, we found that neriifolin provided significant neuroprotection in a neonatal model of hypoxia/ischemia and in a middle cerebral artery occlusion model of transient focal ischemia. "
4.	Prostatic Neoplasms (Prostate Cancer) 01/01/2023 - "Mechanistically, neriifolin suppressed the tumor growth by increasing DNA damage and apoptosis through CHOP-C/EBP-α signaling axis of ERS in prostate cancers. " 01/01/2023 - "We found that cardiac glycoside neriifolin markedly inhibited the cell growth and induced apoptosis in prostate cancer cells. " 01/01/2023 - "Taken together, these results suggest that cardiac glycoside neriifolin may be a potential tumor-specific chemotherapeutic agent in prostate cancer treatment." 01/01/2023 - "Here, we report that cardiac glycoside neriifolin suppresses the malignancy of cancer cells via increasing DNA damage and apoptosis through activation of endoplasmic reticulum stress (ERS) in prostate cancers. " 01/01/2023 - "Cardiac glycoside neriifolin exerts anti-cancer activity in prostate cancer cells by attenuating DNA damage repair through endoplasmic reticulum stress."
5.	Poisoning 11/01/2012 - "Neriifolin LC-MS/MS tests performed on the patient's serum and urine samples confirmed cardenolide poisoning. "

Related Drugs and Biologics

1.	Cardiac Glycosides
2.	oleandrin
3.	Strophanthidin
4.	Digoxin (Digitek)
5.	Digitoxigenin
6.	Cardenolides
7.	cannogenin thevetoside (peruvoside)
8.	thevetine
9.	gitoxigenin
10.	convallatoxin