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5'-deoxy-5-iodotubercidin

from red algae Hypnea valentiae; structure given in first source

Also Known As:

5-DITB

Networked: 5 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Purines: 651
      - Purine Nucleosides: 360
        Tubercidin: 42
        5'-deoxy-5-iodotubercidin: 5
Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleosides: 6847
  - Purine Nucleosides: 360
    - Tubercidin: 42
      - 5'-deoxy-5-iodotubercidin: 5
  - Ribonucleosides: 49
    - Tubercidin: 42
      - 5'-deoxy-5-iodotubercidin: 5

Related Diseases

1.	Hyperalgesia 01/08/1999 - "The present study was conducted to characterize the development of tactile allodynia in the streptozotocin-induced rat model of diabetes, and to evaluate the antinociceptive effects of systemically administered morphine and the adenosine kinase inhibitor, 5'-deoxy-5-iodotubercidin (5'd-5IT) in this model. "
2.	Hypothermia 09/15/1986 - "5'-Deoxy-5-iodotubercidin was previously reported to cause potent muscle relaxation and hypothermia when injected i.p. " 02/01/1984 - "5'-Deoxy-5-iodotubercidin, isolated from the red alga Hypnea valentiae, caused potent muscle relaxation and hypothermia when injected into mice. "
3.	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 02/12/1997 - "The effects of 5'-deoxy-5-iodotubercidin (5'd-5IT), an inhibitor of the adenosine-catabolizing enzyme, adenosine kinase, were studied in male Wistar rats subjected to 2 h of transient middle cerebral artery occlusion. "
4.	Seizures (Absence Seizure) 06/01/1999 - "The AK inhibitors 5'-amino-5'-deoxyadenosine, 5-iodotubercidin, and 5'-deoxy-5-iodotubercidin inhibited maximal electroshock (MES) seizures in rats. "

Related Drugs and Biologics

1.	Adenosine Kinase
2.	Streptozocin (Streptozotocin)
3.	Morphine (MS Contin)
4.	Enzymes
5.	Adenosine (Adenocard)
6.	5'-amino-5'-deoxyadenosine
7.	5-iodotubercidin