lipoxin A4

11/01/2013 - "This study was conducted to elucidate the role of lipoxin A4 in upper airway inflammation. "
01/01/2009 - "A number of studies have demonstrated the effect of LXA4 to counteract inflammation in different cell and animal models, but till now, no relative report about the role of LXs in progress or prevention of AL. Murine RAW264.7 macrophage cell line and MC3T3-E1 osteoblasts (OB) cell line were purchased. "
09/01/2005 - "These emerging studies indicate that the LXA4 circuit may hold a fundamental role in maintaining an ocular environment that actively restricts inflammation while promoting wound healing."
02/15/2000 - "In this study, we report that LXA4 promotes another important step in the resolution phase of inflammation, namely, phagocytosis of apoptotic PMN by monocyte-derived macrophages (Mphi). "
09/01/2015 - "LXA4 induces an anti-inflammatory response, which could participate in the resolution of inflammation."

11/01/2013 - "Lipoxin A4 ameliorates cerebral ischaemia/reperfusion injury through upregulation of nuclear factor erythroid 2-related factor 2."
12/15/2007 - "Lipoxin A4 and annexin-1 failed to prevent reperfusion injury in IL-10-deficient mice. "
03/01/2012 - "A lipoxin A4 analog ameliorates blood-brain barrier dysfunction and reduces MMP-9 expression in a rat model of focal cerebral ischemia-reperfusion injury."
05/01/2013 - "However, the mechanisms by which LXA4 induced protective role on myocardial ischemia/reperfusion injury remains unclear. "
01/01/2013 - "Lipoxin a4 preconditioning and postconditioning protect myocardial ischemia/reperfusion injury in rats."

10/01/2013 - "In late sepsis, treatment with BOC-2 had no effect, but LXA4 improved the survival rate by reducing the excessive inflammatory response, this effect being abolished by pretreatment with BOC-2. "
03/01/2015 - "Effects of Lipoxin A4 on antimicrobial actions of neutrophils in sepsis."
10/01/2013 - "Therefore, a proper interference with LXA4 system may be a new therapeutic avenue to treat sepsis. "
10/01/2013 - "In addition, LXA4 has a dual role in sepsis and that its beneficial or harmful effects are critically dependent on the time. "
10/01/2013 - "Thus, the anti-inflammatory and pro-resolution mediator LXA4 and its receptor FPR2/ALX levels were increased in the early phase of sepsis, contributing to the septic inflammatory dysregulation. "

11/01/2015 - "In this study, we sought to investigate the mechanisms of LXA4 in modulation of ENaC-γ in lipopolysaccharide (LPS)-induced inflammatory lung injury. "
01/01/2013 - "We evaluated the anti-inflammatory and proresolution bioactions of lipoxin A4 in our lipopolysaccharide (LPS-)induced lung injury model. "
08/01/2015 - "In summary, these experiments demonstrated two novel findings: human MSCs promote the resolution of lung injury in mice in part through the proresolving lipid mediator LXA4, and LXA4 itself should be considered as a therapeutic for acute respiratory distress syndrome. "
01/01/2013 - "We demonstrated that lipoxin A4 significantly improved histology of rat lungs and inhibited IL-6 and TNF- α in LPS-induced lung injury. "
01/01/2014 - "We hypothesized that treatment with Resolvin D1 and/or Lipoxin A4 would prevent lung injury in a murine model of BPD. "

05/01/2013 - "However, the mechanisms by which LXA4 induced protective role on myocardial ischemia/reperfusion injury remains unclear. "
01/01/2013 - "Lipoxin a4 preconditioning and postconditioning protect myocardial ischemia/reperfusion injury in rats."
04/01/2013 - "In the present study, we investigated the effect of lipoxin A4 on myocardial ischemia-reperfusion injury (IRI) following cardiac arrest (CA) in a rabbit model. "
04/01/2013 - "Effect of lipoxin A4 on myocardial ischemia reperfusion injury following cardiac arrest in a rabbit model."
05/01/2013 - "Studies have shown that lipoxin A4 (LXA4) and activation of LXA4 receptor provided protection against myocardial ischemia/reperfusion injury in animal models. "