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omeprazole sulfide

omeprazole metabolite; structure given in first source

Also Known As:

H 168-22; omeprazole sulphide

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Sulfur Compounds: 278
  - Sulfoxides: 23
    - 2-Pyridinylmethylsulfinylbenzimidazoles
      - Omeprazole: 3417
        omeprazole sulfide: 1
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyridines: 88
    - 2-Pyridinylmethylsulfinylbenzimidazoles
      - Omeprazole: 3417
        omeprazole sulfide: 1
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzimidazoles: 245
      - 2-Pyridinylmethylsulfinylbenzimidazoles
        Omeprazole: 3417
        omeprazole sulfide: 1

Experts

1.	Daujat-Chavanieu, Martine: 1 article (05/2006)
2.	Fabre, Jean-Michel: 1 article (05/2006)
3.	Gerbal-Chaloin, Sabine: 1 article (05/2006)
4.	Maurel, Patrick: 1 article (05/2006)
5.	Pichard-Garcia, Lydiane: 1 article (05/2006)
6.	Poellinger, Lorenz: 1 article (05/2006)
7.	Sa-Cunha, Antonio: 1 article (05/2006)

Related Diseases

1.

Hepatocellular Carcinoma (Hepatoma)

05/01/2006 - "Omeprazole-sulphide is a pure antagonist of AhR in Hepa-1c1c7 and HepG2 hepatoma cell lines. "
05/01/2006 - "Metabolic LC/MS analysis reveals that omeprazole-sulphide (AhR antagonist) is efficiently converted to omeprazole (AhR activator) by cytochrome P450 CYP3A4, a target gene of PXR, in primary human hepatocytes but not in hepatoma cells in which PXR is not expressed. "

Related Drugs and Biologics

1.	Cytochrome P-450 CYP3A
2.	Omeprazole (Prilosec)
3.	Cytochrome P-450 Enzyme System (Cytochrome P450)