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7- chloro- 5- propyl- 1,2,4- triazolo(4,3- a)quinoxaline- 1,4(2H,5H)- dione
structure given in first source
Also Known As:
REV 3164; REV-3164; RHC 3164; RHC-3164; (1,2,4)Triazolo(4,3-a)quinoxaline-1,4(2H,5H)-dione, 7-chloro-5-propyl-
Networked:
2
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Azoles: 2138
Triazoles: 1533
7-chloro-5-propyl-1,2,4-triazolo(4,3-a)quinoxaline-1,4(2H,5H)-dione: 2
Related Diseases
1.
Anaphylaxis (Anaphylactic Shock)
09/01/1984 - "
REV 3164 (0.01-1 mg/kg i.v. or 10 mg/kg i.p.) abolished rat (IgE) passive lung anaphylaxis (PLA, ED50 = 0.05 mg/kg i.v. for inhibition of elevated airway resistance).
"
01/01/1984 - "
RHC 3164 has been investigated for its antiallergic activities in 3 in vitro models of anaphylaxis.
"
09/01/1984 - "
At 10 mg/kg i.p., REV 3164 did not affect active lung anaphylaxis in guinea-pigs pharmacologically manipulated to enhance the production and action of slow reacting substance of anaphylaxis (SRS-A), nor did it exhibit anticholinergic activity in the rat.
"
2.
Immediate Hypersensitivity
09/01/1984 - "
It is concluded that REV 3164 is an oral inhibitor of IgE-dependent immediate hypersensitivity in the rat with biological activities in rats and guinea-pigs similar to DSCG.
"
3.
Asthma (Bronchial Asthma)
09/01/1984 - "
REV 3164 has been evaluated in a variety of intact rodent models to reveal potential utility in the prophylactic treatment of asthma.
"
Related Drugs and Biologics
1.
Anti-Allergic Agents (Antiallergic Agents)
2.
Cholinergic Antagonists (Anticholinergics)
3.
SRS-A
4.
Immunoglobulin E (IgE)
5.
Dihydrotachysterol (AT 10)