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2'- deoxy- 3',5'- di- O- acetyl- 5- fluoro- 3- (3- methylbenzoyl)uridine

structure given in first source

Also Known As:

FF 705; FF-705

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrimidines: 510
    - Pyrimidine Nucleosides: 50
      - Uridine: 1186
        Deoxyuridine: 331
        Floxuridine: 690
        2'-deoxy-3',5'-di-O-acetyl-5-fluoro-3-(3-methylbenzoyl)uridine: 4
Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleosides: 6847
  - Pyrimidine Nucleosides: 50
    - Uridine: 1186
      - Deoxyuridine: 331
        Floxuridine: 690
        2'-deoxy-3',5'-di-O-acetyl-5-fluoro-3-(3-methylbenzoyl)uridine: 4
  - Deoxyribonucleosides: 34
    - Deoxyuridine: 331
      - Floxuridine: 690
        2'-deoxy-3',5'-di-O-acetyl-5-fluoro-3-(3-methylbenzoyl)uridine: 4

Related Diseases

1.	Neoplasms (Cancer) 03/17/1992 - "FF-705 at 32 mg/kg (the effective dose) suppressed tumor growth to about 40% of the control level. " 01/01/1984 - "Clinical efficacy of new fluorouridine derivative, FF-705, was studied in 108 patients with advanced malignant tumors. " 01/01/1984 - "A phase I study of a new floxuridine derivative, FF-705, was performed in patients with various types of solid tumors. " 04/01/1986 - "Reduction of the tumor weight was greater in mice bearing sarcoma-180 and rats bearing Yoshida sarcoma treated with the oral administration of FF-707 than that FF-705. "
2.	Yoshida Sarcoma 04/01/1986 - "Reduction of the tumor weight was greater in mice bearing sarcoma-180 and rats bearing Yoshida sarcoma treated with the oral administration of FF-707 than that FF-705. "
3.	Sarcoma 180 04/01/1986 - "Reduction of the tumor weight was greater in mice bearing sarcoma-180 and rats bearing Yoshida sarcoma treated with the oral administration of FF-707 than that FF-705. "
4.	Body Weight (Weight, Body) 03/17/1992 - "At this dose, body weight gain was suppressed slightly when FF-705 was given alone, and this change was milder in the DFMO-supplemented group. "

Related Drugs and Biologics

1.	Floxuridine (FUdR)
2.	FF 707

Related Therapies and Procedures

1.	Oral Administration