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ritipenem

carbapenem antibiotic; structure given in first source

Also Known As:

FCE 22101; FCE-22101; ritipenem sodium

Networked: 12 relevant articles (3 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amides: 2428
  - Lactams: 2198
    - beta-Lactams: 2386
      - Carbapenems: 4837
        ritipenem: 12
Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - beta-Lactams: 2386
      - Carbapenems: 4837
        ritipenem: 12

Related Diseases

1.	Respiratory Tract Infections (Respiratory Tract Infection) 03/01/1996 - "[Comparative study on the efficacy of ritipenem acoxil and cefotiam hexetil in chronic lower respiratory tract infections by the double-blind method]." 03/01/1989 - "FCE 22101 and imipenem were very potent against the bacteria studied, including beta-lactamase producing strains, which can be isolated from patients with respiratory tract infections (MIC less than or equal to 8 mg/l). " 03/01/1996 - "To objectively evaluate the efficacy, safety and usefulness of the newly developed penem oral antibiotic, ritipenem acoxil (RIPM-AC), against chronic lower respiratory tract infections, we conducted a multi-center double-blind comparative study using cefotiam hexetil (CTM-HE) as a control drug. "
2.	Intraabdominal Infections 03/01/1989 - "FCE 22101 seems to be useful in the treatment of intra-abdominal infections and deserves further clinical investigation." 03/01/1989 - "Efficacy of FCE 22101 compared with imipenem and with gentamicin plus metronidazole in the treatment of experimental intra-abdominal infections in rats." 03/01/1989 - "This experimental model was used to compare the efficacies of FCE 22101, imipenem, and gentamicin combined with metronidazole in the treatment of intra-abdominal infections. "
3.	Urinary Tract Infections (Urinary Tract Infection) 11/01/1995 - "Dose finding study on the efficacy and safety of ritipenem in complicated urinary tract infections."
4.	Bacteriuria 03/01/1995 - "Subanalyses of bacteriologic outcome showed that failure rates varied between 6% and 67% for ritipenem acoxil and between 1% and 43% for norfloxacin, depending on how significant posttherapy bacteriuria was defined; systematic studies are are clearly needed on how best to define significant posttherapy bacteriuria. " 03/01/1995 - "Five to 9 days after the completion of therapy, persistent bacteriuria was documented in more women given ritipenem acoxil than norfloxacin (95% confidence interval, 0.14; 0.38). " 03/01/1995 - "Interpretation of the bacteriologic outcome of antibiotic treatment for uncomplicated cystitis: impact of the definition of significant bacteriuria in a comparison of ritipenem acoxil with norfloxacin. "
5.	Infections 03/01/1989 - "Activity of FCE 22101 and other beta-lactam antibiotics against experimental genital infections in the rat and mouse." 05/01/1987 - "On the basis of these results, FCE 22101 appears to be a promising antimicrobial agent for treatment of anaerobic infections, and further clinical investigations are indicated." 03/01/1989 - "The therapeutic activities of the parenterally administered penem FCE 22101, cefuroxime and ampicillin were compared in an experimental model of genital infections in progesterone-treated virgin rats and normal female mice. "

Related Drugs and Biologics

1.	Imipenem
2.	beta-Lactamases (beta-Lactamase)
3.	cefotiam hexetil
4.	Metronidazole (Metric)
5.	Gentamicins (Gentamicin)
6.	Norfloxacin
7.	Meropenem (Merrem)
8.	Anti-Bacterial Agents (Antibiotics)
9.	FCE 22891
10.	beta-Lactams

Related Therapies and Procedures

1.	Therapeutics