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centbutindole

RN given refers to cpd without isomeric designation

Also Known As:

centbutindole, (+-)-isomer; centbutindole, (R)-isomer; centbutindole,(S)-isomer

Networked: 4 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrazines: 150
    - centbutindole: 4

Experts

1.	Asthana, O P: 1 article (10/2002)
2.	Chandra, R: 1 article (10/2002)
3.	Dalal, P K: 1 article (10/2002)
4.	Singh, H: 1 article (10/2002)
5.	Srivastava, J S: 1 article (10/2002)

Related Diseases

1.	Schizophrenia (Dementia Praecox) 10/01/2002 - "Comparative efficacy of centbutindole & risperidone in schizophrenia." 10/01/1999 - "A comparative efficacy study of centbutindole and haloperidol in schizophrenia." 01/01/1989 - "Centbutindole vs trifluoperazine: a double-blind controlled clinical study in acute schizophrenia." 10/01/2002 - "The findings of present study shows that Centbutindole could be used as a promising new drug for treatment of schizophrenia in place of a typical antipsychotics as it has shown improvement on negative symptoms similar to risperidone."
2.	Hypothermia 01/01/1988 - "Centbutindole is a new neuroleptic drug having a pharmacological profile similar to haloperidol, but it does not cause hypothermia and has a higher separation between doses causing catalepsy and neurolepsy. "
3.	Catalepsy 01/01/1988 - "Centbutindole is a new neuroleptic drug having a pharmacological profile similar to haloperidol, but it does not cause hypothermia and has a higher separation between doses causing catalepsy and neurolepsy. "
4.	Dopa-responsive Dystonia 10/01/2002 - "The side effect profile was similar in the two drugs except dystonia (5 patients in centbutindole vs 1 patient in risperidone group). "

Related Drugs and Biologics

1.	Risperidone (Risperdal Consta)
2.	Antipsychotic Agents (Antipsychotics)
3.	Haloperidol (Haldol)
4.	Trifluoperazine (Stelazine)