artesunate

05/01/2015 - "Artesunate is the most effective treatment for severe malaria. "
02/01/2013 - "Early referral and treatment with artesunate was highly effective for severe malaria from all species and associated with zero mortality."
01/01/2010 - "Artesunate combined therapies represent the best option for the treatment of malaria and require the development of new methods of analysis. "
12/01/2009 - "The most important of these are: Use of artesunate combination therapy (ACT) as the first line treatment for all confirmed Pf malaria cases, introduction of rapid diagnostic kits for quick diagnosis of Pf cases, promotion of long lasting insecticide treated bed nets (LLINs) in vulnerable population. "
02/01/2007 - "Our findings indicate that artesunate, in addition to being a very effective treatment for uncomplicated malaria, can also sharply reduce the S. "

03/01/1998 - "Oral artesunate is the most effective treatment for uncomplicated hyperparasitaemia in falciparum malaria. "
01/01/1994 - "Artesunate has been shown to be effective against falciparum malaria, but is associated with a high recrudescence rate. "
03/01/2013 - "IV artesunate is now recommended as the first-line treatment for severe falciparum malaria in France."
01/01/2012 - "Intravenous (i.v.) artesunate is now the recommended first-line treatment of severe falciparum malaria in adults and children by WHO guidelines. "
01/01/2012 - "Therapeutic efficacy of artesunate in the treatment of uncomplicated Plasmodium falciparum malaria and anti-malarial, drug-resistance marker polymorphisms in populations near the China-Myanmar border."

10/01/2011 - "Combination therapy of artesunate (100 mg/kg) and China ϕ was found to be highly effective in clearing the blood stage infection of Plasmodium berghei and it also enhanced the mean survival time (28 ± 0 days) of mice. "
09/01/2010 - "Artesunate previously showed a high prophylactic efficacy against schistosome infection, with a protection rate of 100%. "
11/01/2002 - "Evidence for the efficacy of artesunate in asymptomatic Plasmodium malariae infections."
01/01/2000 - "Efficacy of artesunate against Schistosoma mansoni infections in Richard Toll, Senegal."
03/01/2015 - "falciparum infections from artesunate efficacy trials in Bangladesh, Cambodia, Laos, Myanmar, and Vietnam were genotyped at 33 716 genome-wide single-nucleotide polymorphisms (SNPs). "

11/01/2012 - "The overall parasite clearance times were prolonged compared with the clearance times in a previous study at this site in 2006 to 2007, but this did not persist when the evaluation was limited to subjects with a comparable artesunate dose (4 mg/kg/day) and baseline parasitemia from the two studies. "
10/01/2013 - "Suppression of parasitemia by artesunate and methanolic extract of T. "
01/01/2013 - "Fourteen of 52 participants (26.9%) had a measurable parasitemia 72 hours after initiating artesunate treatment. "
03/01/2012 - "Compound 4g presented better activity then the reference artesunate in percentage of inhibition of parasitemia in treated P. "
01/15/2012 - "The total dose of artesunate in each group was 12 mg/kg. The primary end point was the proportion of children clearing ≥ 99% of their admission parasitemia at 24 hours. "

01/01/2000 - "Artesunate is highly effective and safe for the prevention of schistosomiasis."
09/01/2010 - "We aimed to assess the safety and efficacy of an artesunate-based combination drug in the treatment of schistosomiasis. "
07/01/2004 - "The wide-spread use of artesunate against schistosomiasis has to be considered carefully, however, if it is not to compromise the efficacy of the drug as an antimalarial, by increasing the risk of resistance developing in local Plasmodium."
06/01/2014 - "To our knowledge, this is the first report showing that one-day exposure to AQ inhibits the egg production of adult worm pairs at 1-10 μg/ml and induces specific morphological alterations in the worms at 5 and 10 μg/ml. The present findings have important implications for the evaluation of the therapeutic effects of both AQ monotherapy and combination therapy with artesunate on schistosomiasis in clinical field trials. "
08/01/1983 - "[Chemotherapeutic effect of artesunate in experimental schistosomiasis]."