recainam

structure given in first source

Also Known As:

N-(2,6-dimethylphenyl)-N'-(3-(1-methylethylamino)propyl)urea; Wy 42362; Wy-42,362; Wy-42362; recainam hydrochloride; recainam tosylate; Urea, N-(2,6-dimethylphenyl)-N'-(3-((1-methylethyl)amino)propyl)-

Networked: 8 relevant articles (3 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amides: 2428
  - Urea: 15015
    - Phenylurea Compounds: 1
      - recainam: 8
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Phenylurea Compounds: 1
        recainam: 8

Related Diseases

1.	Ventricular Premature Complexes (Premature Ventricular Contraction) 08/01/1987 - "The antiarrhythmic efficacy and safety of oral recainam hydrochloride, a newly synthesized compound, were assessed during a 2-part study of 12 patients with frequent (at least 30/hour) ventricular premature complexes (VPCs). " 08/01/1986 - "The antiarrhythmic efficacy and safety of intravenous recainam, a newly synthesized compound displaying potent class I antiarrhythmic activity, were tested in 10 hospitalized patients with frequent (greater than 30/h) complex ventricular ectopic beats. " 03/15/1993 - "Antiarrhythmic and pharmacokinetic evaluation of intravenous recainam in patients with frequent ventricular premature complexes and unsustained ventricular tachycardia." 04/01/1987 - "Recainam, [N-2,6-dimethylphenyl-N'-3-(1-methylethyl-amino)propylurea] hydrochloride (Wy-42,362), is a new class I antiarrhythmic agent that has been shown to be very effective in suppressing premature ventricular contractions in humans. "
2.	Ventricular Tachycardia 01/01/1989 - "Electrophysiologic effects and efficacy of recainam for sustained ventricular tachycardia." 03/15/1993 - "Antiarrhythmic and pharmacokinetic evaluation of intravenous recainam in patients with frequent ventricular premature complexes and unsustained ventricular tachycardia."
3.	Supraventricular Tachycardia 02/01/1991 - "Electrophysiologic effects and antiarrhythmic efficacy of recainam in patients with supraventricular tachycardia." 02/01/1991 - "To evaluate its electrophysiologic effects and antiarrhythmic efficacy in patients with recurrent supraventricular tachycardia (SVT), programmed electrical stimulation was performed in 10 patients before and after intravenous recainam (loading dose 0.8 mg/kg, infusion 1 mg/kg/h), and in four patients on oral recainam 1,200 mg/day. "
4.	Ventricular Dysfunction 12/01/1987 - "Based on these data, recainam can be safely administered as a loading dose followed by a continuous infusion in patients with stable cardiac disease without significant ventricular dysfunction."
5.	Heart Diseases (Heart Disease) 12/01/1987 - "Recainam was administered as a loading dose of 3 mg/kg/40 minutes followed by a continuous infusion of 0.9 mg/kg/hr for 23 hours and 20 minutes to ten patients with cardiac disease and frequent PVCs (more than 30/hr). " 12/01/1987 - "Based on these data, recainam can be safely administered as a loading dose followed by a continuous infusion in patients with stable cardiac disease without significant ventricular dysfunction."

Related Drugs and Biologics

1.	propylurea
2.	Acecainide