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alifedrine
inotropic cpd; structure given in first source
Also Known As:
D 13625; D-13625; 1-Propanone, 1-cyclohexyl-3-((2-hydroxy-1-methyl-2-phenylethyl)amino)-, (R-(R*,S*))-
Networked:
4
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Amines: 4871
Amino Alcohols: 20
Propanolamines: 4
Phenylpropanolamine: 282
Oxyfedrine: 61
alifedrine: 4
Ethylamines: 5
Phenethylamines: 28
Oxyfedrine: 61
alifedrine: 4
Ketones: 2618
Propiophenones: 1
Oxyfedrine: 61
alifedrine: 4
Alcohols: 595
Amino Alcohols: 20
Propanolamines: 4
Oxyfedrine: 61
alifedrine: 4
Propanols: 3
Propanolamines: 4
Oxyfedrine: 61
alifedrine: 4
Related Diseases
1.
Heart Failure
01/01/1988 - "
A randomized, double-blind, double-crossover, placebo-controlled haemodynamic study was undertaken in patients with Grade II/III (NYHA) cardiac failure to examine the acute effects of intravenous alifedrine, 20 mg and 40 mg (17 patients), and oral 40 mg alifedrine (8 of these patients).
"
01/01/1989 - "
Alifedrine may have a place in the treatment of heart failure as an oral by active, positive inotropic agent.
"
01/01/1989 - "
The haemodynamic effects of single oral doses of alifedrine 40 mg, 50 mg, 60 mg and placebo were compared in 30 patients with mild to moderate heart failure.
"
01/01/1989 - "
Acute haemodynamic effects of different doses of alifedrine in congestive heart failure.
"
01/01/1988 - "
Haemodynamic effects of intravenous and oral alifedrine in patients with cardiac failure.
"
2.
Ventricular Fibrillation
03/15/1988 - "
Following release of a 40 min coronary artery occlusion there was a marked reduction in reperfusion-induced ventricular fibrillation from 75% in controls, to 37% in the alifedrine-treated dogs.
"
Related Drugs and Biologics
1.
Diuretics