sarcolectin

specific for GALACTURONIC ACID, (D)-ISOMER; interferon antagonist protein from hamster sarcoma & normal muscle which agglutinates normal & transformed cells; major ligand in human placenta is Macrophage Migration-Inhibitory Factors;

Also Known As:

Networked: 12 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Gabius, H J: 3 articles (09/2001 - 09/2000)
2.	Schüring, M P: 3 articles (09/2001 - 09/2000)
3.	Achour, Ammar: 2 articles (08/2010 - 03/2002)
4.	Chany, Charles: 2 articles (08/2010 - 03/2002)
5.	Zick, Y: 2 articles (09/2001 - 09/2000)
6.	Kayser, K: 2 articles (10/2000 - 09/2000)
7.	Khazen, Wael: 1 article (08/2010)
8.	M'bika, Jean-Pierre: 1 article (08/2010)
9.	Ilunga, Alain-Jose L: 1 article (03/2002)
10.	Kaba, Aboubacar: 1 article (03/2002)

Related Diseases

1.	Rheumatoid Nodule 01/01/1999 - "In mature rheumatoid nodules binding of sarcolectin was restricted to the periphery of necrotic areas, to endothelial cells and perivascular connective tissue of marginal zones. " 01/01/1999 - "Detection of sarcolectin-specific receptors like the cytokine macrophage migration inhibitory factor in rheumatoid nodules." 01/01/1999 - "The objective of this study was the evaluation of the relation between the N-acetyl-neuraminic acid-binding endogenous lectin sarcolectin and the cytokine macrophage migration inhibitory factor (MIF) during development of rheumatoid nodules (RN) in seropositive rheumatoid arthritis (RA). "
2.	Rheumatoid Arthritis 01/01/1999 - "The objective of this study was the evaluation of the relation between the N-acetyl-neuraminic acid-binding endogenous lectin sarcolectin and the cytokine macrophage migration inhibitory factor (MIF) during development of rheumatoid nodules (RN) in seropositive rheumatoid arthritis (RA). "
3.	Sarcoma (Soft Tissue Sarcoma) 10/01/1990 - "Sarcolectin is an endolectin present in a great variety of conjunctival tissues (muscles, cartilage, sarcomas), but also in brain or placental extracts of vertebrates, including primates. " 11/15/1984 - "Detection of an interferon antagonist, sarcolectin, in human sarcomas and muscles." 10/25/1983 - "Sarcolectin: an interferon antagonist extracted from hamster sarcomas and normal muscles. " 08/01/2010 - "Sarcolectin (SCL) is a 55 kDa protein cross-reacting with a cytokeratin 7 monomer found in placental blood, sarcomas and various tissues. " 11/15/1984 - "In a variety of human sarcomas we detected the presence of a sarcolectin which reversed an established antiviral protection induced by interferon (IFN). "
4.	Neoplasms (Cancer) 01/15/1998 - "In oral cavity cancer, determining the level of acceptor sites for PNA, T antigen, and sarcolectin provides useful information on histopathologic differentiation, clinical staging, and survival. " 01/15/1998 - "Computer-assisted microscopy was employed in a series of 40 oral cavity cancers to determine quantitatively the percentage of positive cells, the staining intensity, and the level of staining heterogeneity for 3 glycohistochemical markers, including peanut agglutinin (PNA), Thomsen-Friedenreich antigen (T antigen) as part of a neoglycoprotein, and sarcolectin. " 10/01/2000 - "Integrated nuclear fluorescence and the expression of binding capacities of carrier-immobilized estradiol, progesterone and testosterone; and of labeled sarcolectin; and the presence of calcyclin were measured in 50 cases with proven malignant pleural effusions (10 mesotheliomas, 40 metastasizing tumors). " 09/01/2000 - "The immunohistochemical and lectin-histochemical examination of the tumors included analysis of the proliferation-associated protein Ki-67, the p53 protein, estrogen and progesterone receptor, sarcolectin as an indicator of the presence of lymphokine macrophage migration inhibitory factor, antibodies and the labeled protein to assess galectin (galactoside-binding animal lectin)-dependent parameters, analysis of tumor vascularization (CD-34), and expression of bcl-2, vimentin, smooth muscle actin, desmin, and keratin. "
5.	Infections 03/01/2002 - "The interferon antagonist sarcolectin in the progress of HIV-1 infection and in AIDS." 09/01/2001 - "To investigate whether the expression of the macrophage migration inhibitory factor (MIF) 1) is detectable, 2) changes in relation to recurrence and infection status, and 3) relates to the levels of expression of growth regulators/differentiation markers, including galectin-1, -3, and -8, retinoid acid receptors (RAR)]-alpha, -beta, and -gamma, binding sites for sarcolectin, and invasion markers (cathepsins -B and -D, and matrix metalloproteinases [MMP]-2, -3, and -9) in human cholesteatomas. "

Related Drugs and Biologics

1.	Macrophage Migration-Inhibitory Factors
2.	Lectins
3.	Acids
4.	Cytokines
5.	Interferons
6.	Proteins (Proteins, Gene)
7.	S100 Calcium Binding Protein A6
8.	Keratin-7 (Cytokeratin 7)
9.	Galectin 1 (LGALS1)
10.	Galectins (Galectin)