sphondin

from Heracleum laciniatum; cause of phototoxicity in patient with vitiligo

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

1.	Erythema 09/01/1983 - "The minimal erythema dose (MED) in the UVB area was approximately 1/3 of that in persons of skin type II. The application of furocoumarins (psoralens) increased light tolerance by 1 MED at 300-310 nm. Action spectrum studies with furocoumarins from Heracleum laciniatum showed the following order of potency: bergapten, pimpinellin, angelicin and sphondin. "
2.	Photoallergic Dermatitis (Photoallergy) 01/01/1982 - "Photoallergy was noted following the fifth exposure in case 1, and the sixth in case 2. Testing with diluted solutions demonstrated allergy to sphondin, isobergapten and pimpinellin."
3.	Inflammation (Inflammations) 11/29/2002 - "We conclude that sphondin may have the therapeutic potential as an anti-inflammatory drug on airway inflammation."
4.	Hypersensitivity (Allergy) 01/01/1982 - "Photoallergy was noted following the fifth exposure in case 1, and the sixth in case 2. Testing with diluted solutions demonstrated allergy to sphondin, isobergapten and pimpinellin."
5.	Carcinoma (Carcinomatosis) 01/01/2007 - "However, xanthotoxin, esculin and sphondin did not inhibit the growth of human bladder carcinoma cell line E-J in this assay condition. "

1.	pimpinellin
2.	Furocoumarins (Furanocoumarins)
3.	5-Methoxypsoralen
4.	angelicin
5.	Methoxsalen (Oxsoralen)
6.	Esculin (Aesculin)