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methylsuccinic acid

RN given refers to cpd without isomeric designation

Also Known As:

2-methylbutanedioic acid; methylsuccinic acid, (+-)-isomer; Butanedioic acid, 2-methyl-

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Acyclic Acids
    - Dicarboxylic Acids: 108
      - Succinates: 13
        methylsuccinic acid: 4

Experts

1.	De Vos, Dirk E: 1 article (04/2017)
2.	Verduyckt, Jasper: 1 article (04/2017)

Related Diseases

1.	isovaleric Acidemia 04/15/1976 - "Urinary methylsuccinic acid excretion was studied in two cases with isovaleric acidemia. " 03/05/1981 - "The demonstration of 4-hydroxyisovaleric acid supports the contention that urinary methylsuccinic acid seen in patients with isovaleric acidemia has arisen by omega-oxidation of isovaleric acid. "
2.	Muscle Hypotonia (Hypotonia) 07/01/1998 - "Ethylmalonic encephalopathy (EE), an organic aciduria of unknown etiology characterized by developmental delay, hypotonia, and vascular instability associated with lactic acidemia and urinary excretion of ethylmalonic acid (EMA) and methylsuccinic acid (MSA), has been described in 11 patients. "
3.	Dehydration (Water Stress) 04/01/2017 - "Highly selective one-step dehydration, decarboxylation and hydrogenation of citric acid to methylsuccinic acid."
4.	Ethylmalonic encephalopathy 07/01/1998 - "Ethylmalonic encephalopathy (EE), an organic aciduria of unknown etiology characterized by developmental delay, hypotonia, and vascular instability associated with lactic acidemia and urinary excretion of ethylmalonic acid (EMA) and methylsuccinic acid (MSA), has been described in 11 patients. "

Related Drugs and Biologics

1.	Citric Acid (Citrate)
2.	ethylmalonic acid (ethylmalonate)
3.	4-hydroxyisovaleric acid
4.	isovaleric acid