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T-kinin
from rat plasma
Also Known As:
Ile-Ser-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg; Ile-Ser-bradykinin; bradykinin, Ile-Ser-; bradykinin, isoleucyl-serine-
Networked:
14
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Amino Acids, Peptides, and Proteins: 1
Proteins: 484843
Intercellular Signaling Peptides and Proteins: 29768
Kinins: 2029
Bradykinin: 3860
T-kinin: 14
Nerve Tissue Proteins: 2
Neuropeptides: 6772
Bradykinin: 3860
T-kinin: 14
Peptides: 82426
Intercellular Signaling Peptides and Proteins: 29768
Kinins: 2029
Bradykinin: 3860
T-kinin: 14
Neuropeptides: 6772
Bradykinin: 3860
T-kinin: 14
Oligopeptides: 519
Bradykinin: 3860
T-kinin: 14
Biological Factors: 2472
Intercellular Signaling Peptides and Proteins: 29768
Kinins: 2029
Bradykinin: 3860
T-kinin: 14
Inflammation Mediators: 1113
Autacoids: 276
Kinins: 2029
Bradykinin: 3860
T-kinin: 14
Related Diseases
1.
Inflammation (Inflammations)
10/01/1988 - "
The results suggest that T-kinin will play an important role in increasing vascular permeability associated with inflammation.
"
09/22/1992 - "
In contrast, treatment of plasma from healthy human subjects (n = 8) and from patients (n = 8) with inflammation due to acute or chronic gastrointestinal disease under the same conditions did not generate any detectable T-kinin immunoreactivity.
"
01/01/1989 - "
3. T-kinin may not be involved in these inflammations, since the deficient strain owns normal plasma level of T-kininogen.
"
10/14/1985 - "
Release of T-kinin and bradykinin in carrageenin induced inflammation in the rat.
"
01/01/1989 - "
During the inflammatory response, free T-kinin is found in the blood and inflammatory fluids indicating that T-kininogenase (T-kgnase) enzymes exist that release T-kinin and perhaps related T-kinins involved in inflammation.
"
2.
Ascites
01/01/1992 - "
Quantification of Ile-Ser-Bradykinin degradation in human serum and ascites.
"
01/01/1989 - "
T-kinin in human ovarian carcinoma ascites.
"
03/15/1991 - "
Degradation of Ile-Ser-Bradykinin by enzymes in human serum and ascites.
"
12/01/1986 - "
Human Ile-Ser-bradykinin, identical with rat T-kinin, is a major permeability factor in ovarian carcinoma ascites.
"
01/01/1992 - "
A leucine aminopeptidase (LAP) and a carboxypeptidase (CP) activity in human serum and malignant ascites degrade Ile-Ser-Bradykinin (ISB = T-Kinin) in two catalytic steps to desArg9Bradykinin.
"
3.
Carcinoma (Carcinomatosis)
01/01/1989 - "
T-kinin in human ovarian carcinoma ascites.
"
12/01/1986 - "
Human Ile-Ser-bradykinin, identical with rat T-kinin, is a major permeability factor in ovarian carcinoma ascites.
"
4.
Gastrointestinal Diseases (Functional Gastrointestinal Disorders)
09/22/1992 - "
In contrast, treatment of plasma from healthy human subjects (n = 8) and from patients (n = 8) with inflammation due to acute or chronic gastrointestinal disease under the same conditions did not generate any detectable T-kinin immunoreactivity.
"
5.
Edema (Dropsy)
01/01/1994 - "
The edema produced by the injection of carrageenan in rat hindpaws was associated with a sevenfold increase of immunoreactive kinins in the inflamed paw extract (from 0.021 +/- 0.007 to 0.141 +/- 0.021 pmol/g tissue; p < 0.01), the immunoreactivity corresponded to BK, kallidin, and T-kinin after HPLC separation.
"
Related Drugs and Biologics
1.
T-kinin
2.
Kininogens (Kininogen)
3.
Kinins
4.
Enzymes
5.
Carrageenan
6.
Bradykinin
7.
Proteins (Proteins, Gene)
8.
Leucyl Aminopeptidase (Peptidase S)
9.
Kallidin
10.
Carboxypeptidases