1- palmitoyl- 2- (10- (4- ((trifluoromethyl)diazirinyl)phenyl)- 8- oxadecanoyl)- sn- glycero- 3- phosphocholine

RN given refers to parent cpd; RN given from first source

Also Known As:

1-palmitoyl-2-(10-(4-((trifluoromethyl)diazirinyl)phenyl)-8-oxadecanoyl)-sn-glycero-3-phosphocholine, (R)-isomer; PTPC

Networked: 21 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azirines
    - 1-palmitoyl-2-(10-(4-((trifluoromethyl)diazirinyl)phenyl)-8-oxadecanoyl)-sn-glycero-3-phosphocholine: 21
Lipids: 114793
- Membrane Lipids: 1591
  - Phospholipids: 11903
    - Glycerophosphates: 118
      - Phosphatidic Acids: 358
        Glycerophospholipids: 689
        Phosphatidylcholines: 2371
        1-palmitoyl-2-(10-(4-((trifluoromethyl)diazirinyl)phenyl)-8-oxadecanoyl)-sn-glycero-3-phosphocholine: 21

Experts

1.	Brenner, Catherine: 5 articles (11/2011 - 12/2003)
2.	Martel, Cécile: 2 articles (11/2011 - 01/2010)
3.	Deniaud, Aurélien: 2 articles (01/2006 - 10/2004)
4.	Jan, Gwenaël: 2 articles (10/2004 - 12/2003)
5.	Mignotte, Bernard: 2 articles (10/2004 - 12/2003)
6.	Verrier, Florence: 2 articles (10/2004 - 12/2003)
7.	Bütikofer, Simon: 1 article (01/2022)
8.	Gnehm, Florian: 1 article (01/2022)
9.	Gubler, Christoph: 1 article (01/2022)
10.	Kretschmer, Eva-Maria: 1 article (01/2022)

Related Diseases

1.	Ascites 01/01/2022 - "Discussion: PTPC is a safe option for refractory ascites in palliative settings with symptom relief in the majority of patients and should be considered early after onset of ascites. "
2.	Neoplasms (Cancer) 01/01/2021 - "Tumor location on mpMRI has a significant association with local tumor recurrence in patients receiving PTPC. " 01/01/2010 - "Therefore, GD3-7 might be a novel mediator of PTPC-dependent apoptosis in cancer cells." 03/01/2005 - "In conclusion, jasmonates act directly on mitochondria derived from cancer cells in a PTPC-mediated manner, and could therefore bypass premitochondrial apoptotic blocks. " 12/01/2003 - "Therefore, targeting of PTPC components may overcome chemoresistance in tumor cells. " 01/01/2002 - "PTPC showed the highest diagnostic accuracy in detecting the number of and accurately localizing the tumors before surgery. "
3.	Insulinoma 01/01/2002 - "We conclude that a combination of PTPC and intraoperative US may be essential for the successful surgical management of insulinomas." 04/01/1988 - "[The application of SAG and PTPC in the localization of insulinoma]." 01/01/2002 - "PTPC and other preoperative procedures (enhanced computed tomography [CT], arteriography, and US) were performed in eight patients with insulinoma based on our experience during the past 18 years. "
4.	Infections 09/01/2005 - "Based on our findings, we propose a model whereby the proapoptotic PB1-F2 protein acts through the mitochondrial PTPC and may play a role in the down-regulation of the host immune response to infection." 12/01/2003 - "In addition, this approach could identify new putative members and regulators of PTPC pro-apoptotic function and new targets of viral protein involved in the modulation of apoptosis during infection."
5.	Mitochondrial Diseases (Mitochondrial Disease) 05/01/2009 - "Since permeability transition pore (PTPC)-mediated mitochondrial dysfunction occurs during pancreatitis, and we have shown that PI prevents PTPC opening, we studied its effects in a model of pancreatitis. "

Related Drugs and Biologics

1.	Cytochromes c (Cytochrome c)
2.	Mitochondrial Permeability Transition Pore
3.	Proteins (Proteins, Gene)
4.	Caspases
5.	Viral Proteins
6.	Phosphates (Orthophosphate)
7.	Insulin (Novolin)
8.	methyl jasmonate

Related Therapies and Procedures

1.	Preoperative Care
2.	Microspheres (Microsphere)
3.	Cryosurgery