heliox

09/01/1997 - "Heliox: a new treatment for life-threatening asthma."
10/01/2006 - "Studies of the efficacy of heliox in patients with severe asthma have shown mixed results. "
03/01/2003 - "To evaluate, by systematic review, the efficacy of heliox on respiratory mechanics and outcomes in patients with acute asthma. "
06/01/2022 - "Heliox for Pediatric Critical Asthma: A Multicenter, Retrospective, Registry-Based Descriptive Study."
09/18/2015 - "Several factors may explain this heterogeneity, including first the limited number of patients in each trial, and the wide differences in the baseline severity of disease between studies, with the modified Wood Clinical Asthma Score (m-WCAS) in infants treated with heliox ranging from less than two to more than seven. "

01/01/2000 - "CONCLUSION: Heliox is a promising treatment for severe airway obstruction with good results in a short period of time, until the final treatment is established."
06/01/2013 - "Similar low-level evidence suggests that heliox is effective in reducing airway pressure and improving ventilation in various forms of lower airway obstruction. "
03/01/2001 - "Safety and efficacy of heliox as a treatment for upper airway obstruction due to radiation-induced laryngeal dysfunction."
01/01/2019 - "Brachycephalic dogs have naturally occurring airway obstruction where heliox might be a useful therapeutic option. "
03/01/2011 - "Helmet-delivered heliox-CPAP in severe upper airway obstruction caused by PHACES syndrome."

12/07/2013 - "In this study, the heliox group's croup scores improved significantly more at all time points from 90 minutes onwards. "
05/01/2012 - "The improvement in croup scores over the first 60 minutes of transport was more rapid in the heliox-treated children (P < 0.001). "
01/01/2002 - "Limited data suggest that heliox is also effective in the short-term management of refractory croup. "
01/01/2021 - "Randomised controlled trials (RCTs) and quasi-RCTs comparing the effect of heliox in comparison with placebo, no treatment, or any active intervention(s) in children with croup. "
10/29/2018 - "Randomised controlled trials (RCTs) and quasi-RCTs comparing the effect of heliox in comparison with placebo or any active intervention(s) in children with croup. "

02/01/2002 - "There was a significant improvement in the patients' perceived dyspnea as measured by the Borg dyspnea scale at 2 h in the heliox group (1.6, 95% CI 0.3-3.0). "
06/01/2011 - "Normoxic heliox reduced respiratory muscle work and relieved dyspnea across all exercise intensities. "
03/01/2003 - "There was also a slight improvement in the dyspnea index (weighted mean difference, 0.60; 95% CI, 0.04 to 1.16) with the use of heliox over airO(2). "
08/01/1999 - "In the heliox group in the first 20 min, there was a significant decrease in dyspnea score and RR (p<0.05), but there were no further significant improvements for the rest of the study. "
05/01/1996 - "Clinical score, dyspnea score, oxygen saturation, heart rate, and respiratory rate, followed by FVC, FEV1, peak expiratory flow rate (PEFR), and, mean midexpiratory flow rate (FEF25-75) were obtained at study entry, 15 min after breathing the first gas mixture (heliox or air per randomization), 15 min after breathing the second mixture, and again 15 min after stopping the second gas mixture (study end values). "

10/01/2022 - "In patients with severe COPD, use of Heliox in exercise retraining did not produce significantly improved endurance. "
06/01/2004 - "Since heliox had no effect on dynamic hyperinflation, the use of this gas mixture, which is costly and cumbersome, does not appear to be beneficial in stable patients with COPD breathing at rest."
10/01/2022 - "Our hypothesis was that severe COPD patients undertaking exercise would show greater improvement in endurance under a heliox mixture (80/20%) than under air alone. "
09/01/2009 - "We assessed the safety, tolerability, and efficacy of heliox and NIV during exercise in patients with severe COPD. "
01/01/2012 - "Therefore, further studies, aimed to the identification of mechanisms conditioning the response of exercising COPD patients to heliox, are warranted, before heliox administration, which is costly and cumbersome, can be routinely used in rehabilitation programs."