heliox

09/01/1997 - "Heliox: a new treatment for life-threatening asthma."
07/01/2011 - "Heliox and forward-leaning posture improve the efficacy of nebulized bronchodilator in acute asthma: a randomized trial."
10/01/2006 - "Studies of the efficacy of heliox in patients with severe asthma have shown mixed results. "
03/01/2003 - "To evaluate, by systematic review, the efficacy of heliox on respiratory mechanics and outcomes in patients with acute asthma. "
01/01/2015 - "Several factors may explain this heterogeneity, including first the limited number of patients in each trial, and the wide differences in the baseline severity of disease between studies, with the modified Wood Clinical Asthma Score (m-WCAS) in infants treated with heliox ranging from less than two to more than seven. "

02/01/2002 - "There was a significant improvement in the patients' perceived dyspnea as measured by the Borg dyspnea scale at 2 h in the heliox group (1.6, 95% CI 0.3-3.0). "
06/01/2011 - "Normoxic heliox reduced respiratory muscle work and relieved dyspnea across all exercise intensities. "
03/01/2003 - "There was also a slight improvement in the dyspnea index (weighted mean difference, 0.60; 95% CI, 0.04 to 1.16) with the use of heliox over airO(2). "
08/01/1999 - "In the heliox group in the first 20 min, there was a significant decrease in dyspnea score and RR (p<0.05), but there were no further significant improvements for the rest of the study. "
12/31/2009 - "Hence, the presence of TEFL has no systematic effects on the respiratory response to heliox, and the heliox-induced decrease of exercise dyspnea is not mainly due to changes in dynamic hyperinflation or TEFL."

06/01/2013 - "Similar low-level evidence suggests that heliox is effective in reducing airway pressure and improving ventilation in various forms of lower airway obstruction. "
03/01/2001 - "Safety and efficacy of heliox as a treatment for upper airway obstruction due to radiation-induced laryngeal dysfunction."
01/01/2015 - "The aim of the study is to conduct an economical analysis comparing total cost of heliox therapy using an open versus a semi-closed circuit in spontaneously breathing patients with airway obstruction. "
03/01/2011 - "Helmet-delivered heliox-CPAP in severe upper airway obstruction caused by PHACES syndrome."
07/01/2007 - "Heliox therapy, alone or combined with noninvasive ventilation, has successfully been used in the treatment of infants and children with respiratory disease such as airway obstruction. "

06/01/2004 - "Since heliox had no effect on dynamic hyperinflation, the use of this gas mixture, which is costly and cumbersome, does not appear to be beneficial in stable patients with COPD breathing at rest."
09/01/2009 - "We assessed the safety, tolerability, and efficacy of heliox and NIV during exercise in patients with severe COPD. "
01/01/2014 - "Heliox as a driving gas to atomize inhaled drugs on acute exacerbation of chronic obstructive pulmonary disease: a prospective clinical study."
01/01/2012 - "Therefore, further studies, aimed to the identification of mechanisms conditioning the response of exercising COPD patients to heliox, are warranted, before heliox administration, which is costly and cumbersome, can be routinely used in rehabilitation programs."
01/01/2012 - "Contrary to these expectations, beneficial effects of heliox in these patients at rest have been reported only sporadically, and the majority of the studies performed until now suggests that heliox is not a therapeutic option in spontaneously breathing resting COPD patients. "

01/01/2013 - "In this study, the heliox group's croup scores improved significantly more at all time points from 90 minutes onwards. "
05/01/2012 - "The improvement in croup scores over the first 60 minutes of transport was more rapid in the heliox-treated children (P < 0.001). "
01/01/2002 - "Limited data suggest that heliox is also effective in the short-term management of refractory croup. "
01/01/2013 - "In another study there was a slight change in croup scores between heliox and controls, with unclear clinical significance. "
02/01/2005 - "Currently, there is insufficient randomised controlled trial evidence to support the role of heliox in the short-term treatment of croup."