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carocainide

structure given in first source

Also Known As:

1-(4,7-dimethoxy-6-(2-(1-pyrrolidinyl)ethoxy)-5-benzofuranyl)-3-methylurea; MD 770207; MD-770207

Networked: 5 relevant articles (1 outcomes, 0 trials/studies)

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Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrrolidines: 115
    - carocainide: 5

Related Diseases

1.	Supraventricular Tachycardia 12/01/1988 - "Carocainide was effective in the short-term treatment of supraventricular tachycardias. "
2.	Body Weight (Weight, Body) 02/01/1984 - "Intravenous administration of 5 mg/kg body weight of carocainide significantly lengthened the following: A-H interval, the shortest atrial pacing cycle length maintaining 1:1 atrioventricular (A-V) nodal conduction, H-V interval, left bundle-ventricle (LB-V) interval, the shortest His bundle pacing cycle length maintaining 1:1 His-Purkinje conduction, QRS duration, right atrial and right ventricular effective refractory periods. " 04/01/1984 - "Carocainide at doses of 2.5, 5 and 7.5 mg/kg body weight i.v. produced the following effects: a significant and dose-related slowing of the idioventricular rate; a non-significant change of the sinus rate at 2.5 and 5 mg/kg b.w.; and a significant decrease of the total number of triggered ventricular beats induced by ventricular pacing during slow norepinephrine infusion. " 12/01/1988 - "In 11 of 12 patients (11 patients with regular atrioventricular reentrant tachycardia incorporating an accessory pathway, one patient with AV node reentry), sustained tachycardia was stopped by intravenous injection of carocainide in a dose of 3.5 mg/kg body weight. "
3.	Tachycardia (Tachyarrhythmias) 12/01/1988 - "In patients of Group II (n = 12), the ability of carocainide to interrupt supraventricular reentrant tachycardia was studied. " 02/01/1986 - "Five other patients with reciprocating nodal tachycardia induced by atrial extrastimuli had their arrhythmia interrupted by the carocainide injection. " 12/01/1988 - "In 11 of 12 patients (11 patients with regular atrioventricular reentrant tachycardia incorporating an accessory pathway, one patient with AV node reentry), sustained tachycardia was stopped by intravenous injection of carocainide in a dose of 3.5 mg/kg body weight. "
4.	Cardiac Arrhythmias (Arrythmia) 02/01/1984 - "These results suggest that carocainide depresses conduction and lengthens refractory periods at atrial and ventricular levels and provide an explanation for the positive effect of this compound against experimental cardiac arrhythmias." 02/01/1986 - "Five other patients with reciprocating nodal tachycardia induced by atrial extrastimuli had their arrhythmia interrupted by the carocainide injection. "
5.	Ventricular Tachycardia 12/01/1988 - "Electrophysiologic and antiarrhythmic effects of the new benzofurane derivative carocainide given intravenously have been studied in normal patients (Group I) and in patients with paroxysmal supraventricular tachycardias (Group II). "

Related Drugs and Biologics

1.	Norepinephrine (Noradrenaline)

Related Therapies and Procedures

1.	Intravenous Administration
2.	Ligation
3.	Intravenous Injections