HOME
PRODUCTS
COMPANY
CONTACT
FAQ
Research
Dictionary
Pharma
Sign Up
FREE
or
Login
Username:
Password:
Remember login
Login
Send password reminder...
butantrone
Also Known As:
10-butyryl dithranol
Networked:
9
relevant articles (
1
outcomes,
2
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Organic Chemicals: 133
Hydrocarbons: 1713
Cyclic Hydrocarbons: 97
Aromatic Hydrocarbons: 291
Polycyclic Aromatic Hydrocarbons: 2020
Anthracenes: 12
Anthrones: 12
Anthralin: 543
butantrone: 9
Polycyclic Compounds: 6
Polycyclic Aromatic Hydrocarbons: 2020
Anthracenes: 12
Anthrones: 12
Anthralin: 543
butantrone: 9
Related Diseases
1.
Psoriasis (Pustulosis Palmaris et Plantaris)
03/01/1984 - "
Clinical trials with butantrone on psoriasis are justified.
"
01/01/1989 - "
Short-contact therapy for psoriasis with 3.9% butantrone (10-butyryl dithranol).
"
01/01/1986 - "
An open clinical trial was carried out using butantrone ointment in the treatment of 10 patients with psoriasis in order to assess staining and irritation in relation to efficacy.
"
01/01/1989 - "
Previous studies have shown that when butantrone and dithranol were used in equimolar gradually increasing concentrations in short-contact therapy for psoriasis the efficacy of butantrone was somewhat lower compared to dithranol.
"
01/01/1987 - "
Comparison of dithranol and butantrone in short contact therapy of psoriasis.
"
2.
Erythema
01/01/1989 - "
In general, the side-effects (erythema and staining) remained weaker on the butantrone-treated side than on the dithranol-treated side.
"
01/01/1987 - "
When short contact treatment is used, erythema and staining with butantrone are weaker than with dithranol.
"
01/01/1987 - "
Both dithranol concentrations produced a markedly stronger increase of blood flow and erythema than any of the butantrone concentrations and a clear dose response when the concentration was raised from 0.1 to 0.5%.
"
01/01/1983 - "
On the whole, erythema, contact temperature and superficial blood flow, as interdependent parameters of cutaneous inflammation, all showed a time-dependent statistically significant correlation to the dose of dithranol and 10-butyryl dithranol.
"
01/01/1983 - "
In equimolar concentrations corresponding to 0.05% dithranol, dithranol caused markedly more erythema and staining than 10-propionyl dithranol and 10-butyryl dithranol, whereas 10-butyryl dithranol irritated and stained less than 10-propionyl dithranol.
"
3.
Papilloma (Papillomatosis)
04/01/1984 - "
In the butantrone groups, there was only one single papilloma with the 1.5 mM concentration plus DMBA.
"
10/01/1986 - "
The first papillomas appeared 8-11 weeks after initiation and the incidences of papillomas at the end of the experiment were 85% (dithranol 3.5 mM), 16% (butantrone 30 mM), 36% (10-isobutyryl dithranol 30 mM) and 50% (10-valeryl dithranol 30 mM).
"
4.
Neoplasms (Cancer)
04/01/1984 - "
The tumor-producing activity of local applications of dithranol, 10-propionyl dithranol and butantrone was studied in 420 female white NMRI mice.
"
10/01/1986 - "
It is concluded that the tumor-producing and skin-irritating activity of dithranol is clearly greater than that of butantrone, 10-isobutyryl dithranol and 10-valeryl dithranol.
"
10/01/1986 - "
The tumor-producing and skin-irritating activity of the antipsoriatic drug dithranol and its 10-acyl analogues butantrone (10-butyryl dithranol), 10-isobutyryl dithranol and 10-valeryl dithranol were studied in 650 SENCAR mice using a two-stage skin carcinogenesis assay.
"
5.
Carcinogenesis
10/01/1986 - "
The tumor-producing and skin-irritating activity of the antipsoriatic drug dithranol and its 10-acyl analogues butantrone (10-butyryl dithranol), 10-isobutyryl dithranol and 10-valeryl dithranol were studied in 650 SENCAR mice using a two-stage skin carcinogenesis assay.
"
Related Drugs and Biologics
1.
Anthralin (Dithranol)
2.
butantrone
3.
10-propionyl dithranol
4.
Ointments (Pastes)
5.
MM 36
6.
10-isobutyryl dithranol
7.
10-valeryl dithranol
Related Therapies and Procedures
1.
Therapeutics