N- (N'- (3- dimethylaminopropyl)- N''- ethylguanyl)- amphotericin B

guanido derivative of amphotericin B

Also Known As:

amphotericin B, N-(N'-(3-dimethylaminopropyl)-N''-ethylguanyl)-; DAPEG; N-(N'-(3-dimethylaminopropyl)-N''-ethylguanyl)amphotericin B; guanido-amphotericin B; Amphotericin B, N-(((3-(dimethylamino)propyl)amino)(ethylamino)methylene)-

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Lactones: 1549
  - Polyketides: 231
    - Macrolides: 4391
      - Amphotericin B: 6619
        N-(N'-(3-dimethylaminopropyl)-N''-ethylguanyl)- amphotericin B: 1

Related Diseases

HIV Infections (HIV Infection)

09/01/1990 - "The compounds amphotericin B methyl ester (AME) and N-(N'-(2-(4'-methylmorpholinio)ethyl)N"-cyclohexyl guanyl) amphotericin B methyl ester (MCG) inhibited HIV infection by 50% at 1 microgram/ml; N-(N'-(3-dimethylaminopropyl)N"-ethyl guanyl) amphotericin B (DAPEG) did so at 5-11 micrograms/ml. While the virus-inhibitory effect of AME was due to an interaction with target lymphocytes, the effect of MCG was due to a direct anti-viral action. "

Related Drugs and Biologics

1.	Amphotericin B (Amphotericin)
2.	methylamphotericin B (AME)