pyrazolone

05/01/1994 - "[Pyrazolone allergy]."
01/01/1988 - "The specificity of the lymphocyte transformation test in a patient with hypersensitivity reactions to pyrazolone compounds. "
04/15/1983 - "Allergy to pyrazolone-drugs were observed in 20 cases during the same period. "
01/01/1981 - "[Hypersensitivity to pyrazolone drugs (author's transl)]."
05/01/1973 - "Immunological evidence of two forms of allergy to pyrazolone drugs."

04/01/2014 - "The adjusted odds ratio (OR) of having a severe attack for being a migrant was 2.45, having a fever >39°C (OR 5.77), visiting a private clinic (OR 2.65), longer time from symptom onset to diagnosis (OR 1.49), visiting a doctor (OR 1.51), early use of intramuscular pyrazolone (OR 3.36), early use of intravenous glucocorticoids (OR 2.28), or the combination of both (OR 3.75). "
06/01/2010 - "Glucocorticoid and pyrazolone treatment of acute fever is a risk factor for critical and life-threatening human enterovirus 71 infection during an outbreak in China, 2008."
11/14/1983 - "The major antipyretic agents, acetaminophen, aspirin, and pyrazolone derivatives, are equally effective in reducing fever. "
06/01/1972 - "The antipyretic effect of pyrazolone derivatives and salicylates on fever induced with leukocytic or bacterial pyrogen."

03/01/1993 - "Certain adverse reactions to aspirin (ASA), nonsteroidal anti-inflammatory drugs (NSAIDs) and pyrazolone derivatives resemble IgE-mediated hypersensitivity. "
11/01/2019 - "Basophil activation test (BAT) results varied accordingly to the class of the drug studied, and have promising results in immediate hypersensitivity reactions to pyrazolone (selective reactors), neuromuscular blockers, beta-lactams, and platinum compounds, all examples of classical IgE-mediated hypersensitivity drug reactions. "

08/22/2011 - "The results show that the two compounds exhibit improved photochromic performance in coloration and thermal bleaching rates, excellent photostability, high fatigue resistance, and reversible fluorescence switching properties in the solid state in comparison to reported pyrazolone thiosemicarbazones. "
10/05/2016 - "We demonstrate a new strategy for designing reversibility, fatigue resistance and fluorescence switching materials, which are based on pyrazolone derivatives by introducing a pyridine ring. "

08/29/2022 - "Zinc(II) Complex with Pyrazolone-Based Hydrazones is Strongly Effective against Trypanosoma brucei Which Causes African Sleeping Sickness."