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silybin dihemisuccinate
Networked:
4
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Pyrans: 130
Benzopyrans: 195
Chromones: 159
Flavonoids: 9773
Flavonolignans: 40
Silymarin: 1151
Silybin: 995
silybin dihemisuccinate: 4
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Benzopyrans: 195
Chromones: 159
Flavonoids: 9773
Flavonolignans: 40
Silymarin: 1151
Silybin: 995
silybin dihemisuccinate: 4
Related Diseases
1.
Liver Diseases (Liver Disease)
02/25/1985 - "
The flavonoid silybin dihemisuccinate is an antihepatotoxic principle used in the treatment of many liver diseases; its mechanism of action has been ascribed to its antioxidant properties.
"
05/01/1992 - "
Silybin dihemisuccinate sodium salt, a flavonoid used in human therapy of liver dysfunction, has an inhibitory effect in vivo on radiation-induced deactivation of enzymes and peroxidation of membrane lipids in rat liver microsomes.
"
2.
Hemolysis
10/01/1987 - "
Silybin dihemisuccinate protects rat erythrocytes against phenylhydrazine-induced lipid peroxidation and hemolysis.
"
3.
Body Weight (Weight, Body)
02/01/1976 - "
application of 140.5 mg silybin-dihemisuccinate/kg body weight dissolved in phosphate buffer, and 10 min after i.v. administration of [1-14C]-acetate in comparison with rats treated with solvent only, a statistically significant enhancement of specific activities of total liver lipids, free hepatic cholesterol, liver triglycerides, total liver phospholipids, and the hepatic fraction of phosphatidyl ethanolamine can be measured.
"
Related Drugs and Biologics
1.
Flavonoids
2.
Ethanolamine (Colamine)
3.
Triglycerides (Triacylglycerol)
4.
Solvents
5.
Sodium
6.
Salts
7.
Phospholipids (Phosphatides)
8.
Phosphates (Orthophosphate)
9.
Membrane Lipids
10.
Lipids
Related Therapies and Procedures
1.
Therapeutics