Helix lectin

06/01/1994 - "Helix pomatia agglutinin binding in human tumour cell lines: correlation with pulmonary metastases in nude mice."
05/01/2005 - "The lectin Helix pomatia agglutinin as a marker of metastases--clinical and experimental studies."
02/09/1998 - "Reactivity of the N-acetylgalactosamine-binding Helix pomatia agglutinin (HPA) in tumours has been associated with poor prognosis and metastasis development. "
01/01/2006 - "In severe combined immunodeficient mice, metastasizing human breast cancer cell lines were identified by their ability to bind the lectin Helix pomatia agglutinin, which was identified as a marker of metastasis in clinical studies. "
10/15/1996 - "The Helix pomatia agglutinin (HPA)-binding glycoproteins from primary breast cancers and their metastases were compared with appropriate normal control tissues on Western blots. "

09/01/1993 - "An immunohistochemical study of helix pomatia agglutinin binding on carcinomas of the esophagus."
12/01/1991 - "Helix pomatia agglutinin binding activity is a predictor of survival time for patients with gastric carcinoma."
07/01/2010 - "Lectin histochemical study of cell surface glycoconjugate in gastric carcinoma using helix pomatia agglutinin."
10/01/1996 - "In particular, expression of binding sites for the lectin Helix pomatia agglutinin (HPA), which has been shown to be an index of metastatic potential in several human carcinomas, was found on the primary tumour as well as on tumour cells grown in SCID mice, indicating that HPA might be a prognostic indicator in ovarian carcinoma as well. "
06/01/1994 - "Silver stained nucleolar organizer region proteins and Helix pomatia agglutinin immunostaining in esophageal carcinoma: correlated prognostic factors."

11/01/2011 - "MAF-levels of healthy individuals and cancer patients were analysed according to their Gc-phenotype using a Helix pomatia agglutinin-based ELISA. "
06/10/2011 - "Helix pomatia agglutinin (HPA), the lectin from the albumen gland of the Roman snail, has been used in histochemical studies relating glycosylation changes to the metastatic potential of solid tumors. "
04/06/2019 - "The lectin Helix pomatia agglutinin (HPA) recognizes altered glycosylation in solid cancers and the identification of HPA binding partners in tumour tissue and serum is an important aim. "
05/15/2012 - "The lectin Helix pomatia agglutinin (HPA) has been shown to bind aggressive metastatic cancer and was produced in recombinant form (His- and RFP-tagged). "
01/01/2012 - "The lectin from Helix pomatia, (Helix pomatia agglutinin [HPA]), can detect changes in protein glycosylation associated with aggressive metastatic cancer. "

03/01/1995 - "In particular, binding of the lectin from the Roman snail, Helix pomatia agglutinin (HPA), to breast cancer cells is linked with a poor prognosis. "
03/01/1995 - "Lectin-binding properties of human breast cancer cell lines and human milk with particular reference to Helix pomatia agglutinin."
01/01/1995 - "Ultrastructural localization of Helix pomatia agglutinin (HPA)-binding sites in human breast cancer cell lines and characterization of HPA-binding glycoproteins by western blotting."
01/01/2006 - "In severe combined immunodeficient mice, metastasizing human breast cancer cell lines were identified by their ability to bind the lectin Helix pomatia agglutinin, which was identified as a marker of metastasis in clinical studies. "
01/28/2013 - "Helix pomatia agglutinin (HPA) is known to bind aberrant glycans associated with metastatic breast cancer, and was used here to isolate glycoproteins from pooled breast cancer serum samples of (i) patients with recurrent breast cancer and (ii) patients with no sign of recurrence 5years after diagnosis of their primary tumour. "

02/02/2010 - "As the human HT 29 colon cancer cells are positive for the lectin Helix pomatia agglutinin (HPA), which identified the metastatic phenotype in earlier clinical studies, these results are of particular clinical relevance."
10/01/2007 - "Helix pomatia agglutinin (HPA) is a lectin that has been used extensively in histopathology, since its binding to tissue sections from breast and colon cancers is correlated with the worst prognosis for the patients. "
09/01/1997 - "The binding of the lectin Helix pomatia agglutinin (HPA) has been associated with a poor prognosis in breast and colon cancer patients. "
11/01/1994 - "This was true for the lectin Helix pomatia agglutinin (HPA), the binding of which is associated with a high metastatic potential in some human tumours, including colon cancer. "
11/01/1994 - "Glycosylation patterns of the human colon cancer cell line HT-29 detected by Helix pomatia agglutinin and other lectins in culture, in primary tumours and in metastases in SCID mice."