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11 alpha- hydroxy- 9,15- dioxo- 2,3,4,5,20- pentanor- 19- carboxyprostanoic acid

Subscribe to New Research on 11 alpha-hydroxy-9,15-dioxo-2,3,4,5,20-pentanor-19-carboxyprostanoic acid

major urinary metabolite of PGE in man

Also Known As:

HDOPNP; PGE-MUM; Cyclopentaneoctanoic acid, 2-(2-carboxyethyl)-5-hydroxy-epsilon,3-dioxo-, (1R-(1alpha,2beta,5beta))-

Networked: 5 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Lipids: 18571
- Fatty Acids: 6864
  - Prostanoic Acids
    - 11 alpha-hydroxy-9,15-dioxo-2,3,4,5,20-pentanor-19-carboxyprostanoic acid: 5

Experts

1.	Ito, Satoru: 2 articles (07/2014 - 01/2014)
2.	Okayasu, Isao: 2 articles (07/2014 - 01/2014)
3.	Matsuura, Masaaki: 2 articles (07/2014 - 01/2014)
4.	Fujiwara, Mutsunori: 2 articles (07/2014 - 01/2014)
5.	Arihiro, Seiji: 1 article (07/2014)
6.	Saruta, Masayuki: 1 article (07/2014)
7.	Arai, Yoshinori: 1 article (07/2014)
8.	Tajiri, Hisao: 1 article (07/2014)
9.	Matsuoka, Mika: 1 article (07/2014)
10.	Kato, Tomohiro: 1 article (07/2014)

Related Diseases

1.	Ulcerative Colitis 01/01/2000 - "PGE-MUM was determined by a simplified immunoassay of bicyclic PGE-MUM and analyzed for the influence of laxative administration and active/remission phases of ulcerative colitis. " 01/01/2000 - "The PGE-MUM levels were significantly correlated with our modified Talstad scores, clinical disease activity indices in ulcerative colitis. "
2.	Colitis 01/01/2000 - "It was confirmed by time course studies of individual patients that changes in PGE-MUM correlated well with colitis activity. "
3.	Inflammation 07/01/2014 - "Compared with CRP level, PGE-MUM level demonstrated better sensitivity for reflecting UC activity, especially in cases of histologic inflammation, and thus seems to be a better evaluator of mucosal healing. " 01/01/2014 - "This RIA method for PGE-MUM may be thus a sensitive and reliable biomarker for current inflammation, different from serum CRP." 07/01/2014 - "Since prostaglandin E2 production and colonic inflammation are associated, we evaluated whether prostaglandin E-major urinary metabolite (PGE-MUM) can be used as such a biomarker. " 05/20/1983 - "In the early phase of inflammation, the excretion of PGE-MUM and PGF-MUM was suppressed by administration of indomethacin. "
4.	Experimental Arthritis 02/01/1980 - "3) Prednisolone and azathiopurine, which suppressed both primary and secondary lesions, increased the excretion of PGE-MUM over adjuvant control values on days 4 and 8. The facts described above suggest that the increase of endogenous PGE during days 4 to 8 may be important in the suppression of secondary lesions in adjuvant arthritis in rats."

Related Drugs and Biologics

1.	Dinoprostone (PGE2)
2.	Prostaglandins E (PGE)
3.	Prednisolone (Predate)
4.	Indomethacin (Indometacin)
5.	azathiopurine
6.	prostaglandin F-main urinary metabolite