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nicotinamide N-oxide

Networked: 6 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyridines: 88
    - Nicotinic Acids: 13
      - Niacinamide: 2223
        nicotinamide N-oxide: 6
- Heterocyclic Acids
  - Nicotinic Acids: 13
    - Niacinamide: 2223
      - nicotinamide N-oxide: 6

Experts

1.	Huang, Lianzhou: 1 article (01/2022)
2.	Jia, Jiaoyan: 1 article (01/2022)
3.	Li, Feng: 1 article (01/2022)
4.	Qing, Shurong: 1 article (01/2022)
5.	Ren, Zhe: 1 article (01/2022)
6.	Song, Xiaowei: 1 article (01/2022)
7.	Wang, Shuai: 1 article (01/2022)
8.	Wang, Yifei: 1 article (01/2022)
9.	Wang, Yiliang: 1 article (01/2022)
10.	Wang, Yuan: 1 article (01/2022)

Related Diseases

1.	Inflammation (Inflammations) 12/16/2022 - "In the present study, we investigated the effect of nicotinamide n-oxide (NAMO), a metabolite mainly produced by gut microbe, on HSV-1-induced microglial inflammation and HSE. " 12/16/2022 - "Nicotinamide n-Oxide Attenuates HSV-1-Induced Microglial Inflammation through Sirtuin-1/NF-κB Signaling."
2.	Herpes Simplex Encephalitis (Herpes Encephalitis) 01/01/2022 - "The intestinal microbial metabolite nicotinamide n-oxide prevents herpes simplex encephalitis via activating mitophagy in microglia." 01/01/2023 - ": AD: Alzheimer disease; ABX: antibiotics; HSE: herpes simplex encephalitis; HSV-1: herpes simplex virus type 1; NAD+: nicotinamide adenine dinucleotide; NAMO: nicotinamide n-oxide; SCFAs: short-chain fatty acids."
3.	Weight Gain 07/01/2012 - "Based on the changes in urinary metabolites, the slow rate of weight gain in mice fed the HCD related to activation of the tricarboxylic acid cycle (resulting in increased levels of citrate and succinate in HCD mice), while the HFD affected nicotinamide metabolism (increased levels of 1-methylnicotineamide, nicotinamide-N-oxide in HFD mice), which leads to systemic oxidative stress. "
4.	Neoplasms (Cancer) 12/01/2016 - "We identified the following potential drug targets against induced resistance of cancer cells towards chemotherapy by methotrexate (MTX): TGFalpha, IGFBP7, alpha9-integrin, and the following chemical compounds: zardaverine and divalproex as well as human metabolites such as nicotinamide N-oxide."
5.	Infections 01/01/2022 - "Furthermore, exogenous administration of nicotinamide n-oxide (NAMO), an oxidative product of nicotinamide derived from gut microbiota, to ABX-treated or untreated HSE mice significantly diminished microglia-mediated proinflammatory response and limited HSV-1 infection in CNS. "

Related Drugs and Biologics

1.	Niacinamide (Nicotinamide)
2.	Sirtuin 1
3.	Succinic Acid (Succinate)
4.	Citric Acid (Citrate)
5.	Transforming Growth Factor alpha (TGF-alpha)
6.	Valproic Acid (Depakote)
7.	NAD (NADH)
8.	Methotrexate (Mexate)
9.	Volatile Fatty Acids
10.	Anti-Bacterial Agents (Antibiotics)

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)