oxymatrine

01/01/2015 - "Oxymatrine (OMTR) is widely used for the treatment of chronic hepatitis B (CHB) in China. "
05/01/2002 - "Oxymatrine is effective in treating chronic hepatitis B. "
10/01/2004 - "Oxymatrine is an effective and safe agent for the treatment of chronic hepatitis B."
11/01/2003 - "Oxymatrine is an effective and safe agent for the treatment of chronic hepatitis B."
10/01/2004 - "A total of 144 patients with chronic hepatitis B entered the study for 52 weeks; of them 72 received oxymatrine, and 72 received a placebo. "

12/01/2015 - "Accumulating evidence indicated that oxymatrine (OMT), an alkaloid compound from the Chinese medicinal herb Sophora flavescens, exhibits activity against hepatic fibrosis. "
06/01/2014 - "Liposomal oxymatrine in hepatic fibrosis treatment: formulation, in vitro and in vivo assessment."
02/14/2014 - "Oxymatrine (OM) is an alkaloid extracted from a Chinese herb that has been found to possess an anti-hepatic fibrosis effect, although its anti-fibrotic potential is limited due to a lack of targeting specificity, a short half-life and adverse effects. "
01/01/2014 - "The results indicate that oxymatrine improves intestinal barrier function via NF-κB-mediated signaling pathway and may be used as a new protecting agent for cirrhosis-associated intestinal mucosal damage. "
06/01/2013 - "To investigate whether oxymatrine (OM) could promote mesenchymal stem cell (MSC) therapy in CCl4-induced hepatic fibrosis (HF) in rats and to initially explore its mechanisms. "

05/01/2009 - "[An experimental study of protective effects of ischemic preconditioning and oxymatrine on lung ischemia reperfusion injury]."
09/01/2014 - "To investigate the protective effects of oxymatrine (OMT) on lung ischemia reperfusion injury (LIRI) in rabbits, models of LIRI in rabbit were used. "
05/01/2009 - "To investigate the protective effects of ischemic preconditioning (IPC) and oxymatrine (OMT) on lung ischemia reperfusion injury (LIRI) in rabbit. "
06/01/2015 - "Oxymatrine ameliorates renal ischemia-reperfusion injury from oxidative stress through Nrf2/HO-1 pathway."
01/01/2011 - "The present study was designed to investigate the potential effect of oxymatrine in ischemia-reperfusion injury in rat's brain and to explore the possible role of oxymatrine in Nrf2 pathway. "

01/01/2013 - "Our data demonstrate that oxymatrine reduces LPS-induced NF-κB nuclear translocation and activity independently of IκBα status, prevents intestinal inflammation through blockade of inflammatory signaling and ameliorates overall intestinal inflammation in vivo."
01/01/2013 - "Oxymatrine prevents NF-κB nuclear translocation and ameliorates acute intestinal inflammation."
01/01/2011 - "To study the effect of oxymatrine (Oxy) on airway inflammation and the distribution of dendritic cells (DC) in lung and spleen tissues of asthmatic mice. "
01/01/2013 - "We investigated the impact of oxymatrine in an acute model of intestinal injury and inflammation. "
08/01/2008 - "The inflammation was markedly ameliorated in the oxymatrine-treated rats. "

04/01/2002 - "To evaluate the protective effects and mechanism of action of oxymatrine (OM) on the experimental fulminant hepatitis (FH) and early hepatocyte apoptosis in murine liver tissue. "
05/15/2014 - "Oxymatrine, a quinolizidine alkaloid, has been widely used for the treatment of hepatitis. "
08/30/2012 - "Oxymatrine is extracted from the traditional Chinese herb Sophora flavescens Ait, possesses anti-inflammatory, anti-oxidative and anti-apoptotic properties, and has been used for the treatment of chronic viral hepatitis and many other diseases. "
03/01/2011 - "Oxymatrine (OMTR) is an anti-hepatitis drug used in China. "
04/01/2002 - "Two separate experiments were designed, including saline control group, fulminant hepatitis group and oxymatrine pretreated group (50 mg/kg, intraperitoneally, bid x 3 days). "