HOME
PRODUCTS
COMPANY
CONTACT
FAQ
Research
Dictionary
Pharma
Sign Up
FREE
or
Login
Username:
Password:
Remember login
Login
Send password reminder...
2-fluoroestradiol
in contrast to 4-fluoroestradiol above cpd is not a carcinogen
Networked:
4
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Polycyclic Compounds: 6
Fused-Ring Compounds
Steroids: 70059
Estranes
Estrenes
Estradiol: 14115
2-fluoroestradiol: 4
Hormones, Hormone Substitutes, and Hormone Antagonists
Hormones: 80400
Gonadal Hormones: 716
Gonadal Steroid Hormones: 7657
Estradiol Congeners: 358
Estradiol: 14115
2-fluoroestradiol: 4
Related Diseases
1.
Neoplasms (Cancer)
09/01/1986 - "
After 7 months, 75% of the estradiol-treated hamsters had kidney tumors, while in animals exposed to 2-fluoroestradiol renal carcinoma could not be detected.
"
06/01/1994 - "
17 beta-Estradiol is known to induce kidney tumors in male Syrian hamsters when administered chronically, whereas 4-fluoroestradiol does so only after an extended induction period and 2-fluoroestradiol is not carcinogenic; both fluorinated analogs are hormonally active.
"
04/01/1993 - "
In male Syrian hamsters, an animal model for estradiol-induced carcinogenesis, 2-fluoroestradiol was not carcinogenic, whereas 4-fluoroestradiol induced kidney tumors after a prolonged latency period, compared with estradiol (100% tumor incidence), when the compounds were administered to hamsters in hormonally equipotent doses.
"
2.
Carcinogenesis
04/01/1993 - "
In male Syrian hamsters, an animal model for estradiol-induced carcinogenesis, 2-fluoroestradiol was not carcinogenic, whereas 4-fluoroestradiol induced kidney tumors after a prolonged latency period, compared with estradiol (100% tumor incidence), when the compounds were administered to hamsters in hormonally equipotent doses.
"
09/01/1986 - "
To understand the mechanism of hormonal carcinogenesis, estrogen-induced renal carcinoma in male Syrian hamsters was investigated using estradiol and 2-fluoroestradiol.
"
3.
Renal Cell Carcinoma (Grawitz Tumor)
09/01/1986 - "
After 7 months, 75% of the estradiol-treated hamsters had kidney tumors, while in animals exposed to 2-fluoroestradiol renal carcinoma could not be detected.
"
09/01/1986 - "
To understand the mechanism of hormonal carcinogenesis, estrogen-induced renal carcinoma in male Syrian hamsters was investigated using estradiol and 2-fluoroestradiol.
"
4.
Carcinoma (Carcinomatosis)
03/01/1983 - "
2-Fluoroestradiol, a modified estrogen, did not induce renal clear-cell carcinoma in male Syrian hamsters despite its estrogenic potency, which is comparable to that of estradiol.
"
Related Drugs and Biologics
1.
Estradiol (Delestrogen)
2.
Estrogens (Estrogen)
3.
4-fluoroestradiol