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2- aminomethyl- 4- tert- butyl- 6- propionylphenol

structure given in first source

Also Known As:

ONO 3144; ONO-3144; 1-Propanone, 1-(3-(aminomethyl)-5-(1,1-dimethylethyl)-2-hydroxyphenyl)-

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Ketones: 2618
  - Propiophenones: 1
    - 2-aminomethyl-4-tert-butyl-6-propionylphenol: 4

Experts

1.	Endo, Hiroshi: 1 article (05/2002)
2.	Higashino, Hideak: 1 article (05/2002)
3.	Kawamoto, Masazumi: 1 article (05/2002)
4.	Lee, Wen-Hsiung: 1 article (05/2002)
5.	Maeda, Kana: 1 article (05/2002)

Related Diseases

1.	Stroke (Strokes) 05/01/2002 - "Beneficial effects of long-term administration of ONO-3144, a free radical scavenger, on stroke-prone SHR." 05/01/2002 - "To clarify the preventive effects of ONO-3144, a free radical scavenger, on stroke-prone spontaneously hypertensive rats (SHRSP) and free radicals related to the hypertensive disorders. "
2.	Myocardial Reperfusion Injury 12/01/1990 - "Prevention of myocardial reperfusion injury in experimental coronary revascularization following ischemic arrest by a novel antiinflammatory drug, ONO-3144."
3.	Hypertension (High Blood Pressure) 05/01/2002 - "The oxidative f ree radicals closely relate to hypertension-induced pathophysiological changes in SHRSP, and ONO-3144 prevents the changes of those disorders, and then brings longevity."
4.	Hemolysis 02/01/1983 - "Unlike IM, phenylbutazone (PB) and tiaramide (TI), ONO-3144 showed marked inhibitory effects on H2O2-induced hemolysis and lipid peroxidation. "
5.	Edema (Dropsy) 02/01/1983 - "In the carrageenin test the activity of ONO-3144 was comparable to that of indomethacin (IM), while in the dextran, albumin, yeast and scald edema test it was more potent than that of IM. "

Related Drugs and Biologics

1.	Free Radical Scavengers
2.	Phenylbutazone (Butazolidin)
3.	Free Radicals
4.	Dextrans (Dextran)
5.	Carrageenan
6.	Albumins
7.	1- (4- chlorobenzoyl)- 3- (2- (1H- imidazol- 1- yl)- 2- oxoethyl)- 5- methoxy- 2- methyl- 1H- indole
8.	tiaramide