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2',3'-dideoxycytidine 5'-triphosphate
inhibits vesicular stomatitis virus RNA synthesis
Also Known As:
2',3'-ddCTP; ddCTP-2',3'; Triphosphoric acid, P-((5-(4-amino-2-oxo-1(2H)-pyrimidinyl)tetrahydro-2-furanyl)methyl) ester, (2S-cis)-
Networked:
3
relevant articles (
1
outcomes,
0
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Pyrimidines: 510
Pyrimidine Nucleotides: 48
Cytosine Nucleotides: 10
Deoxycytosine Nucleotides
2',3'-dideoxycytidine 5'-triphosphate: 3
Nucleic Acids, Nucleotides, and Nucleosides: 1
Nucleotides: 15763
Deoxyribonucleotides: 132
Deoxycytosine Nucleotides
2',3'-dideoxycytidine 5'-triphosphate: 3
Pyrimidine Nucleotides: 48
Cytosine Nucleotides: 10
Deoxycytosine Nucleotides
2',3'-dideoxycytidine 5'-triphosphate: 3
Dideoxynucleotides: 3
2',3'-dideoxycytidine 5'-triphosphate: 3
Related Diseases
1.
Murine Acquired Immunodeficiency Syndrome (MAIDS)
11/01/1993 - "
In an attempt to overcome these limitations, we have tested the efficacy of the oral administration of 2',3'-dideoxycytidine (DDC) and the administration of its phosphorylated derivative, 2',3'-dideoxycytidine 5'-triphosphate (DDCTP) encapsulated into autologous red blood cells in a murine retrovirus-induced immunodeficiency model of AIDS (MAIDS).
"
2.
Acquired Immunodeficiency Syndrome (AIDS)
11/01/1993 - "
In an attempt to overcome these limitations, we have tested the efficacy of the oral administration of 2',3'-dideoxycytidine (DDC) and the administration of its phosphorylated derivative, 2',3'-dideoxycytidine 5'-triphosphate (DDCTP) encapsulated into autologous red blood cells in a murine retrovirus-induced immunodeficiency model of AIDS (MAIDS).
"
3.
Vesicular Stomatitis
03/01/1983 - "
Inhibition of vesicular stomatitis virus RNA synthesis by 2',3'-dideoxycytidine 5'-triphosphate.
"
03/01/1983 - "
The ability of the compound 2',3'-dideoxycytidine 5'-triphosphate (ddCTP) to serve as an inhibitor of viral RNA synthesis was examined using an in vitro system that supports vesicular stomatitis virus (VSV) protein synthesis, transcription and replication.
"
4.
Disease Progression
07/01/1997 - "
In vivo administration of 2',3'-dideoxycytidine 5'-triphosphate (ddCTP) encapsulated into autologous erythrocytes to LP-BM5-infected mice was found to reduce infectivity and disease progression.
"
Related Drugs and Biologics
1.
Zalcitabine (Hivid)
2.
Viral RNA
3.
Proteins (Proteins, Gene)
Related Therapies and Procedures
1.
Oral Administration