HLA-A28 antigen

this antigen specificity is found on HLA-A*68 and HLA-A*69 allele families

Also Known As:

HLA A28; HLA-28 antigen; HLA-A28

Networked: 23 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Carbohydrates: 22023
- Glycoconjugates: 1353
  - Glycoproteins: 24834
    - Membrane Glycoproteins: 2252
      - Histocompatibility Antigens Class I: 1944
        HLA-A Antigens: 2452
        HLA-A28 antigen: 23
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Glycoproteins: 24834
    - Membrane Glycoproteins: 2252
      - Histocompatibility Antigens Class I: 1944
        HLA-A Antigens: 2452
        HLA-A28 antigen: 23
  - Membrane Proteins: 10078
    - Membrane Glycoproteins: 2252
      - Histocompatibility Antigens Class I: 1944
        HLA-A Antigens: 2452
        HLA-A28 antigen: 23
Biological Factors: 2472
- Antigens: 143924
  - Surface Antigens: 5813
    - Histocompatibility Antigens: 1132
      - HLA Antigens: 8934
        HLA-A Antigens: 2452
        HLA-A28 antigen: 23
      - Histocompatibility Antigens Class I: 1944
        HLA-A Antigens: 2452
        HLA-A28 antigen: 23
  - Isoantigens: 1221
    - Histocompatibility Antigens: 1132
      - HLA Antigens: 8934
        HLA-A Antigens: 2452
        HLA-A28 antigen: 23
      - Histocompatibility Antigens Class I: 1944
        HLA-A Antigens: 2452
        HLA-A28 antigen: 23

Experts

1.	Abraham, Georgi: 1 article (11/2015)
2.	Ali, Asik Ali Mohammed: 1 article (11/2015)
3.	Mathew, Milly: 1 article (11/2015)
4.	Mehra, Nikita: 1 article (11/2015)
5.	Nagarajan, Prethivee: 1 article (11/2015)
6.	Ramachandran, A: 1 article (11/2015)
7.	Reddy, Pooja P: 1 article (11/2015)
8.	Reddy, Yogesh N V: 1 article (11/2015)
9.	Reddy, Yuvaram N V: 1 article (11/2015)
10.	Sundaram, Varun: 1 article (11/2015)

Related Diseases

1.	Chronic Kidney Failure (Chronic Renal Failure) 09/01/2014 - "While the HLA-B8 antigen may be a susceptibility risk factor for development of ESRD, the HLA-A28, and HLA-DR11 antigens may be protective against development of ESRD in Kuwaiti population." 09/01/2014 - "The frequency of HLA-B8 antigen was significantly higher in ESRD patients (OR = 2.62, p = 0.001, pc = 0.038), and the frequency of HLA-A28, HLA-DR11 antigens was significantly higher in healthy controls (OR 0.42, p = 0.0001; pc = 0.0021, and OR = 0.44, p = 0.0007, pc = 0.01 respectively). "
2.	Psoriasis (Pustulosis Palmaris et Plantaris) 09/01/2011 - "Furthermore, the frequencies of HLA-A28 (OR-0.074, P=0.0024), B5 (OR-0.059, P<0.0001), B12 (OR-0.051, P=0.0002), and B15 (OR-0.237, P=0.0230) were significantly decreased in psoriasis patients. " 09/01/2011 - "This study shows the strong association of HLA-A2, B8, and B17 antigens with psoriasis conferring susceptibility to psoriasis patients from Western India, while the antigens HLA-A28, B5, and B12 show strong negative association with the disease."
3.	Genetic Predisposition to Disease (Genetic Predisposition) 06/01/1997 - "These results confirm the role of HLA-DR4 (DRB1*0407) in the genetic susceptibility to AP and raise the possibility of a role for class I MHC antigens HLA-A28 and B16 in Mexican patients." 03/01/1996 - "A genetic predisposition to this disease has been reported in subjects with phenotype HLA-DR3, -DR4, -A1, -B8 or HLA-A28, -B8; a phenotype HLA-B8 has been described in subjects with adrenal autoantibodies (AA) not progressing toward an overt disease. "
4.	Neoplasms (Cancer) 04/01/2013 - "HLA-A28 allele was overrepresented in patients with malignancy (11 vs 2 %, p = 0.006). " 02/15/1996 - "The expression of HLA expression was reduced in two tumors [1 x HLA-A1(pT2); 1 x HLA-A28 (pT2)]. "
5.	Melanoma (Melanoma, Malignant) 07/01/1993 - "Of the 28 cytolytic CD8+ T cell clones, 21 lysed the autologous melanoma cell line (M7) but not the autologous lymphoblastoid cell line (LCL-7) nor the two melanoma cell line, M1 (HLA A28) and M2 (HLA A28, A31), used to immunize the patient. " 04/15/2002 - "An association between expression of > or = two of five HLA class I antigens (HLA-A2, HLA-A28, HLA-B44, HLA-B45, and HLA-C3; collectively called M5) and response to an allogeneic melanoma vaccine (Melacine; Corixa Corporation, Seattle, WA) has been described in stage IV melanoma. "

Related Drugs and Biologics

1.	Antigens
2.	HLA-B8 Antigen (HLA B8 Antigen)
3.	HLA-DR11 antigen
4.	HLA-A2 Antigen (HLA A2 Antigen)
5.	HLA-B44 Antigen
6.	HLA-B13 Antigen
7.	HLA-B5 antigen
8.	HLA-B51 Antigen
9.	HLA-A11 Antigen
10.	HLA-DR4 Antigen (HLA DR4 Antigen)