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valerenic acid

a saturated oplopanone type indene from Valeriana officinalis

Networked: 6 relevant articles (1 outcomes, 0 trials/studies)

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Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Sesquiterpenes: 1370
      - valerenic acid: 6
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Indenes: 4
        valerenic acid: 6
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Indenes: 4
    - valerenic acid: 6

Experts

1.	Boran, Tuğçe: 1 article (01/2022)
2.	Kara, Mehtap: 1 article (01/2022)
3.	Keskin, Seda Eren: 1 article (01/2022)
4.	Kuzmin, Sergei V: 1 article (01/2022)
5.	Sevim, Çiğdem: 1 article (01/2022)
6.	Tsatsakis, Aristides M: 1 article (01/2022)
7.	Veskoukis, Aristidis S: 1 article (01/2022)
8.	Öztaş, Ezgi: 1 article (01/2022)
9.	Berumen, Laura Cristina: 1 article (06/2020)
10.	Escobar-Cabrera, Jesica Esther: 1 article (06/2020)

Related Diseases

1.	Anxiety Disorders (Anxiety Disorder) 11/20/2017 - "coli production platform will serve as the foundation for the synthesis of novel valerenic acid analogues potentially useful for the treatment of anxiety disorders."
2.	Metabolic Syndrome (Dysmetabolic Syndrome X) 02/02/2023 - "The inhibitory effects of the extracts, valerenic acid derivatives and phenolic acids, on metabolic syndrome (MS)-related enzymes activities were further examined. "
3.	Neurodegenerative Diseases (Neurodegenerative Disease) 01/01/2022 - "Valerenic acid (VA), a sesquiterpenoid of the plant Valeriana officinalis, has attracted attention of the research community due to its potential positive role against neurodegenerative diseases induced by chemicals. "
4.	Seizures (Absence Seizure) 07/14/2015 - "Valerenic acid and Valeriana officinalis extracts delay onset of Pentylenetetrazole (PTZ)-Induced seizures in adult Danio rerio (Zebrafish)."
5.	Parkinson Disease (Parkinson's Disease) 06/01/2020 - "Valerenic acid prevents neuroinflammation in a Parkinson's disease mouse model, which might reflect the neuroprotection of dopaminergic neurons with the recovery of motor ability." 06/01/2020 - "A 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride (MPTP)-induced mouse model of Parkinson's disease was developed to evaluate the motor effects of valerenic acid. " 06/01/2020 - ""Effect of valerenic acid on neuroinflammation in a MPTP-induced mouse model of Parkinson's disease"." 06/01/2020 - "The results indicate that the use of valerenic acid as a co-treatment decreases the neuroinflammation in Parkinson's disease induced by MPTP and provides evidence of a decrease in the evaluated pro-inflammatory cytokines and in the amount of GFAP in the mesencephalic area. "

Related Drugs and Biologics

1.	Cytokines
2.	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)
3.	Sesquiterpenes
4.	Serotonin Receptors
5.	Pentylenetetrazole (Metrazol)
6.	Enzymes
7.	Acids