replitase

a multienzyme complex of mammalian cells; produces deoxynucleoside triphosphates and delivers them to the DNA polymerase activity, which also resides in the complex

Also Known As:

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Murthy, Shalini: 2 articles (09/2010 - 12/2006)
2.	Barrack, Evelyn R: 1 article (09/2010)
3.	Kim, Sahn-Ho: 1 article (09/2010)
4.	Sivanandam, Arun: 1 article (09/2010)
5.	Veer Reddy, G Prem: 1 article (09/2010)
6.	Reddy, G Prem-Veer: 1 article (12/2006)

Related Diseases

1.

Prostatic Neoplasms (Prostate Cancer) 09/01/2010 - "We propose that a detailed understanding of the structural interactions between AR and the components of pre-RC and replitase may lead to the development of new strategies for the treatment of prostate cancer." 12/01/2006 - "In addition, we show that androgen receptor (AR), which plays a critical role in proliferation and viability of prostate cancer cells, is associated with replitase, and that identification of constituents of replitase in androgen-dependent versus androgen-independent prostate cancer cells may provide insights into androgen-regulated events that control proliferation of prostate cancer cells and potentially offer an effective strategy for the treatment of prostate cancer."

Related Drugs and Biologics

1.	Androgen Receptors (Androgen Receptor)
2.	Androgens