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endodeoxyribonuclease NdeI

from Neisseria dentrificans; cleaves DNA at 5'-CATATG-3' sequence

Also Known As:

NdeI endonuclease

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Esterases: 1574
      - Deoxyribonucleases: 1259
        Endodeoxyribonucleases
        DNA Restriction Enzymes: 848
        Type II Site-Specific Deoxyribonucleases
        endodeoxyribonuclease NdeI: 1
      - Endonucleases: 1227
        Endodeoxyribonucleases
        DNA Restriction Enzymes: 848
        Type II Site-Specific Deoxyribonucleases
        endodeoxyribonuclease NdeI: 1
  - DNA Restriction-Modification Enzymes: 41
    - DNA Restriction Enzymes: 848
      - Type II Site-Specific Deoxyribonucleases
        endodeoxyribonuclease NdeI: 1

Experts

1.	Chang, Shwu-Fen: 1 article (01/2011)
2.	Lee, Hsien-Hsiung: 1 article (01/2011)

Related Diseases

1.

Congenital Adrenal Hyperplasia (Hyperplasia, Congenital Adrenal)

01/01/2011 - "The most frequent bimodular RCCX module of the RP1-C4A-CYP21A1P-TNXA-RP2-C4B-CYP21A2-TNXB gene sequence is located on chromosome 6p21.3. To determine RCCX alterations, we used the polymerase chain reaction (PCR) product containing the tenascin B (TNXB) and CYP21A2 genes with TaqI digestion and Southern blot analysis with AseI and NdeI endonuclease digestion of genomic DNA from congenital adrenal hyperplasia patients with common mutations resulting from an intergenic conversion of CYP21A1P, such as an I2 splice, I172N, V281L, F306-L307insT, Q318X, and R356W, and dual mutations of I236N/V237E in the CYP21A2 gene. "

Related Drugs and Biologics

1.	Tenascin
2.	DNA (Deoxyribonucleic Acid)