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hemoglobin Osler

Tyr replaced by Asp at position 145 on beta chain

Also Known As:

Hb Nancy; Hb Osler; hemoglobin Nancy; Hemoglobin Osler

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Blood Proteins: 12459
    - Hemoglobins: 37188
      - Abnormal Hemoglobins: 120
        hemoglobin Osler: 3
  - Hemeproteins: 194
    - Globins: 2716
      - Hemoglobins: 37188
        Abnormal Hemoglobins: 120
        hemoglobin Osler: 3

Related Diseases

1.

Polycythemia (Erythrocytosis)

12/01/1982 - "Despite the increase in whole blood viscosity associated with erythrocytosis, our data do not support the use of therapeutic phlebotomy to improve exercise performance in patients with hemoglobin Osler."
03/01/1975 - "Polycythemia in a black woman was associated with hemoglobin Osler. "
03/01/1975 - "Polycythemia produced by hemoglobin Osler (beta-145 (HC2) Tyr yields Asp)."
05/01/1998 - "Three hemoglobin variants (Hb Nancy, Osler and Fort Gordon), carrying the same Tyr-->Asp substitution at position beta 145 (HC2), have been independently described in 1975 in patients with marked polycythemia. "

Related Drugs and Biologics

1.	Hemoglobins (Hemoglobin)