beta-amyrin

alpha-amyrin is also available; a 5 ring triterpene derived from oleanane that differs from alpha-amyrin in having the 29-carbon at the 20 position; RN given refers to (3 beta)-isomer

Networked: 12 relevant articles (2 outcomes, 5 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Chaves, M H: 3 articles (08/2008 - 12/2007)
2.	Santos, F A: 3 articles (08/2008 - 12/2007)
3.	Cunha, G M A: 2 articles (08/2008 - 02/2008)
4.	Holanda Pinto, S A: 2 articles (08/2008 - 02/2008)
5.	Pinto, L M S: 2 articles (08/2008 - 02/2008)
6.	Rao, V S: 2 articles (08/2008 - 02/2008)
7.	Chaves, Mariana H: 2 articles (01/2006 - 10/2005)
8.	Oliveira, Francisco A: 2 articles (01/2006 - 10/2005)
9.	Rao, Vietla S N: 2 articles (01/2006 - 10/2005)
10.	Silva, Regilane M: 2 articles (01/2006 - 10/2005)

Related Diseases

1.	Pancreatitis 09/14/2010 - "To study the beneficial effects of triterpene alpha,beta-amyrin and the underlying mechanisms in an experimental pancreatitis model. " 09/14/2010 - "alpha,beta-amyrin has the potential to combat acute pancreatitis by acting as an anti-inflammatory and antioxidant agent." 09/14/2010 - "alpha,beta-amyrin, a natural triterpenoid ameliorates L-arginine-induced acute pancreatitis in rats." 09/14/2010 - "Acute pancreatitis was induced in five groups of rats (n = 8) by L-arginine (2 x 2.5 g/kg, intraperitoneal, 1 h apart) and 1 h later, they received a single oral dose of alpha,beta-amyrin (10, 30 and 100 mg/kg), methylprednisolone (30 mg/kg) and vehicle (3% Tween 80). "
2.	Visceral Leishmaniasis (Kala Azar) 07/15/2005 - "The efficacy of 18beta-glycyrrhetinic acid (GRA), a pentacyclic triterpene belonging to the beta-amyrin series of plant origin, was evaluated in experimental visceral leishmaniasis. "
3.	Inflammation (Inflammations) 02/01/2008 - "These results provide evidence to show that alpha, beta-Amyrin retards acute inflammation in rat model of periodontitis and warrant further study on its efficacy to prevent chronic periodontitis-associated bone loss." 07/01/2010 - "and its component beta-amyrin are able to block most of the iNOS protein functions and NO induction, and could therefore be new selective NO inhibitors with great potential in treating arthritis inflammation." 12/01/2007 - "Modulation of acute visceral nociception and bladder inflammation by plant triterpene, alpha, beta-amyrin in a mouse model of cystitis: role of tachykinin NK(1)-receptors, and K(+)(ATP) channels."
4.	Chronic Periodontitis 02/01/2008 - "These results provide evidence to show that alpha, beta-Amyrin retards acute inflammation in rat model of periodontitis and warrant further study on its efficacy to prevent chronic periodontitis-associated bone loss."
5.	Periodontitis 02/01/2008 - "This study was aimed to evaluate the anti-inflammatory potential of triterpene alpha, beta-amyrin in rats on acute phase periodontitis. " 02/01/2008 - "These results provide evidence to show that alpha, beta-Amyrin retards acute inflammation in rat model of periodontitis and warrant further study on its efficacy to prevent chronic periodontitis-associated bone loss." 02/01/2008 - "Anti-inflammatory effect of alpha, beta-Amyrin, a pentacyclic triterpene from Protium heptaphyllum in rat model of acute periodontitis." 02/01/2008 - "Rats were sacrificed at 24 h, and the gingival tissue analysed for myeloperoxidase (MPO) and thiobarbituric acid-reactive substances (TBARS), as measures of neutrophil influx and lipid-peroxidation, respectively alpha, beta-Amyrin as well as dexamethasone significantly inhibited the periodontitis-associated increases of TNF-alpha, and the gingival MPO and TBARS. "

Related Drugs and Biologics

1.	Triterpenes
2.	Arginine (L-Arginine)
3.	18alpha-glycyrrhetinic acid
4.	Opioid Analgesics (Opioids)
5.	Hydrogen
6.	Pentacyclic Triterpenes
7.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
8.	Dexamethasone (Maxidex)
9.	Cyclophosphamide (Cytoxan)
10.	Capsaicin (Zostrix)

Related Therapies and Procedures

1.	Analgesia