fibrin fragment D (D-dimer)

06/15/2004 - "A clinical prediction rule for pulmonary embolism is most helpful when it is used with subsequent evaluations such as ventilation-perfusion scanning, D-dimer testing, or computed tomography. "
05/01/2009 - "The purpose of our study was to investigate whether D-dimer screening is being used effectively to determine the need for MDCT in diagnosing acute pulmonary embolism (PE) in emergency department patients. "
05/01/2011 - "Recently, a diagnostic strategy using a clinical decision rule, D-dimer testing and spiral computed tomography (CT) was found to be effective in the evaluation of patients with clinically suspected pulmonary embolism (PE). "
01/11/2006 - "A diagnostic management strategy using a simple clinical decision rule, D-dimer testing, and CT is effective in the evaluation and management of patients with clinically suspected pulmonary embolism. "
06/01/2013 - "There is therefore an urgent need for the evaluation of diagnostic strategies that safely exclude the diagnosis of acute pulmonary embolism in pregnant women without the need for diagnostic imaging, which is currently the gold standard, as no studies have confidently demonstrated the safety of ruling out VTE by clinical probability assessment combined with the use of D-dimer levels. "

01/01/2003 - "Because of its high negative predictive value, D-Dimer is an important parameter in the exclusion of deep vein thrombosis (DVT) but it produces a high number of false-positive results. "
01/01/2002 - "Quantitative d-dimer levels may be very helpful in establishing the diagnosis of venous thrombosis. "
02/01/1999 - "D-dimer positive patients had significantly greater frequencies of venous thromboses (21.9% vs 4.8%, p = 0.035). "
10/17/1998 - "To investigate the efficacy of using a rapid plasma D-dimer test as an adjunct to compression ultrasound for diagnosing clinically suspected deep vein thrombosis. "
10/01/2012 - "D-dimer (DD) assays are effective for the exclusion of deep-vein thrombosis (DVT), but point-of-care (POC) DD assays have not been fully evaluated. "

08/01/2007 - "D-dimer values decreased and nearly normalized in clinically cured patients during a long-term follow-up period, a finding consistent with completion of thrombosis and cure of the disease. "
01/01/2003 - "Current data suggest that increased plasma D-dimer levels can be clinically helpful in predicting the presence of prosthetic valve thrombus. "
04/01/2008 - "However, evidence for the efficacy of diagnosing thrombosis based on the D-dimer levels is still not well established. "
09/01/2014 - "Although D-dimer is now regarded as the biochemical gold standard for assisting the diagnosis of VTE and predicting the recurrent risk of thrombosis, the interpretation of D-dimer values with increasing age remains challenging due to many factors. "
11/01/2005 - "Whilst a negative test is helpful in ruling out thrombosis, the significance and determinants of an elevated plasma D-dimer level in otherwise healthy subjects are poorly understood. "

11/01/2010 - "Several lines of evidence now attest that the global diagnostic performances of some D-dimer assays largely outperform those of any other coagulation or fibrinolytic marker proposed thus far, and a "negative" D-dimer measured with rapid enzyme linked fluorescent immunoassay is now considered the biochemical gold standard for ruling out an acute episode of venous thromboembolism in a patient with a low pretest probability for venous thromboembolism, so that additional testing can be safely omitted. "
02/01/2005 - "D-dimer (DD) measurement has proved to be very useful to exclude venous thromboembolism (VTE) in outpatients. "
09/01/2010 - "The PROLONG randomized study showed that patients with an abnormal D-dimer after anticoagulation suspension for a first unprovoked episode of venous thromboembolism (VTE) benefited from anticoagulation resumption. "
07/10/2014 - "D-dimer to guide the duration of anticoagulation in patients with venous thromboembolism: a management study."
04/01/2014 - "D-dimer as a predictor of venous thromboembolism in acutely ill, hospitalized patients: a subanalysis of the randomized controlled MAGELLAN trial."

04/01/2014 - "Patients with cardioembolism had the highest level of plasma D-dimer and they suffered the most serious neurological deficit and the worst outcome among the five subtypes, the difference was statistically significant (F = 5.34; P = 0.012); while the lacunar stroke patients had the best outcome with the lowest level of D-dimer. "
11/01/1999 - "The measurement of D-dimer concentration may help to better decide the indications for therapy of the patients with ischemic stroke of undetermined etiology."
03/01/2009 - "Is D-dimer helpful in evaluating stroke patients? "
04/01/2014 - "The present study aims to test whether plasma d-dimer levels could predict comorbid malignancy in patients with ischemic stroke. "
04/01/2014 - "The goal of this study is to explore the relationship between the plasma D-dimer level and the outcome of acute ischemic stroke patients among different stroke subtypes. "