Aspergillus restrictus MITF protein (mitogillin)

a phosphodiesterase making it a Ribonuclease distinguishing it from ribosome inactivating protein that deadenylate; a ribotoxin from Aspergillus; MW 16 kDa; sequence 85% identity to alpha-sarcin

Also Known As:

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Ebel, Frank: 2 articles (07/2014 - 11/2005)
2.	Schwienbacher, Monika: 2 articles (07/2014 - 11/2005)
3.	Beck, Julia: 1 article (07/2014)
4.	Broniszewska, Marzena: 1 article (07/2014)
5.	Heesemann, Jürgen: 1 article (11/2005)
6.	Regula, Jörg T: 1 article (11/2005)
7.	Thies, Svenja: 1 article (11/2005)
8.	Weig, Michael: 1 article (11/2005)
9.	Frosch, M: 1 article (05/2001)
10.	Gross, U: 1 article (05/2001)

Related Diseases

1.	Aspergillosis 05/01/2001 - "We proved the immunogenic capacity of mitogillin in a rabbit animal model, indicating its usefulness as an antigen for serological diagnosis of invasive aspergillosis. " 05/01/2001 - "In serum samples of patients suffering from aspergilloma (AO; n = 32), invasive pulmonary aspergillosis (IPA; n = 42), or invasive disseminated aspergillosis (IDA; n = 40), a good correlation of production of IgG antibody against mitogillin and clinical disease was observed (for patients with AO, 100% [32 of 32] were positive; for patients with IPA, 64% [31 of 42] were positive; for patients with IDA, 60% [24 of 40] were positive). " 11/01/2005 - "Using recombinant mitogillin and chitosanase we detected anti-chitosanase and antimitogillin antibodies in sera of patients suffering from invasive aspergillosis or aspergilloma, but not in control sera of healthy individuals. " 07/01/1991 - "We show by cloning and nucleotide sequence analysis that the 18kDa antigen found in the urine of patients suffering from aspergillosis is related to the fungal protein toxins restrictocin and mitogillin. "
2.	Invasive Pulmonary Aspergillosis 05/01/2001 - "In serum samples of patients suffering from aspergilloma (AO; n = 32), invasive pulmonary aspergillosis (IPA; n = 42), or invasive disseminated aspergillosis (IDA; n = 40), a good correlation of production of IgG antibody against mitogillin and clinical disease was observed (for patients with AO, 100% [32 of 32] were positive; for patients with IPA, 64% [31 of 42] were positive; for patients with IDA, 60% [24 of 40] were positive). "
3.	Neoplasms (Cancer) 04/01/1971 - "Evaluation of mitogillin (NSC-69529) in the treatment of naturally occurring canine neoplasms."
4.	Mycoses (Diseases, Fungus) 07/01/2014 - "IgG responses were found to both proteins, but elevated antibody levels to CsnB and/or mitogillin showed no correlation to the results of the galactomannan antigen assay or clinical signs that are characteristic for fungal infections. "
5.	Infections 11/01/2005 - "This suggests that chitosanase, like mitogillin, is expressed during infection and might therefore be of diagnostic relevance."

Related Drugs and Biologics

1.	Antigens
2.	Proteins (Proteins, Gene)
3.	Immunoglobulin G (IgG)
4.	Antibodies
5.	chitosanase
6.	galactomannan