HOME
PRODUCTS
COMPANY
CONTACT
FAQ
Research
Dictionary
Pharma
Sign Up
FREE
or
Login
Username:
Password:
Remember login
Login
Send password reminder...
butyl 3-(1H-tetrazol-5-yl)oxanilate
orally active antiallergic agent; structure given in first source
Also Known As:
((3-(1H-tetrazol-5-yl)phenyl)amino)oxoacetic acid N-butyl ester; WP 833; WP-833; butyl-((3-(1H-tetrazol-5-yl)phenyl)amino)oxoacetate
Networked:
3
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Azoles: 2138
Tetrazoles: 14
butyl 3-(1H-tetrazol-5-yl)oxanilate: 3
Related Diseases
1.
Hypersensitivity (Allergy)
04/01/1990 - "
The effects of WP-833 metabolites on experimental allergic reactions were investigated in various animal models.
"
01/01/1988 - "
In contrast to above findings demonstrating that WP-833 clearly inhibited type I allergic reaction, systemic Forssman shock in guinea pigs and reversed cutaneous anaphylaxis in rats (type II), passive Arthus reaction in rats (type III), and contact dermatitis and tuberculin reaction in mice (type IV) were unaffected by WP-833 even in higher doses than in those capable of completely inhibiting type I allergic reaction.
"
2.
Shock
01/01/1988 - "
In contrast to above findings demonstrating that WP-833 clearly inhibited type I allergic reaction, systemic Forssman shock in guinea pigs and reversed cutaneous anaphylaxis in rats (type II), passive Arthus reaction in rats (type III), and contact dermatitis and tuberculin reaction in mice (type IV) were unaffected by WP-833 even in higher doses than in those capable of completely inhibiting type I allergic reaction.
"
3.
Contact Dermatitis (Eczema, Contact)
01/01/1988 - "
In contrast to above findings demonstrating that WP-833 clearly inhibited type I allergic reaction, systemic Forssman shock in guinea pigs and reversed cutaneous anaphylaxis in rats (type II), passive Arthus reaction in rats (type III), and contact dermatitis and tuberculin reaction in mice (type IV) were unaffected by WP-833 even in higher doses than in those capable of completely inhibiting type I allergic reaction.
"
4.
Asthma (Bronchial Asthma)
01/01/1988 - "
Experimental asthma was clearly inhibited in a dose-dependent fashion by oral administration of WP-833.
"
5.
Arthus Reaction
01/01/1988 - "
In contrast to above findings demonstrating that WP-833 clearly inhibited type I allergic reaction, systemic Forssman shock in guinea pigs and reversed cutaneous anaphylaxis in rats (type II), passive Arthus reaction in rats (type III), and contact dermatitis and tuberculin reaction in mice (type IV) were unaffected by WP-833 even in higher doses than in those capable of completely inhibiting type I allergic reaction.
"
Related Drugs and Biologics
1.
Tuberculin (PPD)
Related Therapies and Procedures
1.
Oral Administration