phomopsin

Fungal toxins produced by DIAPORTHE TOXICA and PHOMOPSIS LEPTOSTROMIFORMIS. Causes MYCOTOXIC LUPINOSIS in animals.

Also Known As:

phomopside A; phomopside B; phomopsin A; phomopsin B; phomopsins

Networked: 6 relevant articles (0 outcomes, 0 trials/studies)

1.	Poisoning 10/01/1987 - "About 10% of the sheep differed substantially from the rest of the flock in their susceptibility to phomopsin poisoning." 07/01/1987 - "Phomopsins comprise a family of peptide mycotoxins containing a 13-membered ring formed by an ether bridge, produced by the fungus Phomopsis leptostromiformis, the causal agent in lupin poisoning (lupinosis). "
2.	Carcinogenesis 10/01/1990 - "Biliary hyperplasia and carcinogenesis in chronic liver damage induced in rats by phomopsin."
3.	Liver Diseases (Liver Disease) 01/01/2017 - "Phomopsin A (PHO-A), produced by the fungus Diaporthe toxica, is a mycotoxin known to be responsible for fatal liver disease of lupin-fed sheep. "
4.	Leukemia 06/15/1990 - "Dolastatin 10 inhibited the growth of L1210 murine leukemia cells in culture, with a concordant rise in the mitotic index, and its IC50 value for cell growth was 0.5 nM. Comparable values for the other drugs were 0.5 nM for maytansine, 1 nM for rhizoxin, 20 nM for vinblastine, and 7 microM for phomopsin A. "
5.	Hyperplasia 10/01/1990 - "Biliary hyperplasia and carcinogenesis in chronic liver damage induced in rats by phomopsin."

1.	Mycotoxins
2.	Vinblastine (Vinblastine Sulfate)
3.	Steroids
4.	Peptides (Polypeptides)
5.	Maytansine (Maitansine)
6.	Hormones (Hormone)
7.	Ether (Diethyl Ether)
8.	dolastatin 10
9.	ivalin
10.	rhizoxin